全国范围内的临床试验组织：早期乳腺癌的管理
Organization of clinical trial on national scale: management of early cancer of the breast.
作者信息
Baum M, Edwards M H, Magarey C J
出版信息
Br Med J. 1972 Nov 25;4(5838):476-8. doi: 10.1136/bmj.4.5838.476.
Abstract
From a study of the organization of a national clinical trial on the management of early cancer of the breast in women there appear to be overwhelming advantages in studying large numbers of patients. To this end centres abroad have been encouraged to join. All the evidence at present suggests that it is feasible to organize a study on this scale, that the documentation and follow-up are accurate, and that the enthusiasm of the participants can be successfully fostered and maintained.
摘要
通过对一项关于女性早期乳腺癌治疗的全国性临床试验组织情况的研究发现，研究大量患者似乎具有压倒性的优势。为此，国外的中心已被鼓励加入。目前所有证据表明，组织这样规模的研究是可行的，记录和随访是准确的，并且参与者的积极性能够得到成功培养和维持。
相似文献
1
Organization of clinical trial on national scale: management of early cancer of the breast.全国范围内的临床试验组织：早期乳腺癌的管理
Br Med J. 1972 Nov 25;4(5838):476-8. doi: 10.1136/bmj.4.5838.476.
2
3
Management of the axilla in women with breast cancer: current clinical practice and a new selective targeted approach.乳腺癌女性腋窝的处理：当前临床实践及一种新的选择性靶向方法
Ann Surg Oncol. 2008 May;15(5):1282-96. doi: 10.1245/s10434-008-9863-8. Epub 2008 Mar 11.
4
Treatment of early breast cancer: the organization of a 'national trial'.
Br J Surg. 1971 Nov;58(11):861.
5
Postoperative radiotherapy and late mortality: evidence from the Cancer Research Campaign trial for early breast cancer.术后放疗与晚期死亡率：来自癌症研究运动早期乳腺癌试验的证据。
BMJ. 1989 Jun 17;298(6688):1611-4. doi: 10.1136/bmj.298.6688.1611.
6
Conservative surgical treatment of carcinoma of the breast.乳腺癌的保守性手术治疗
Proc R Soc Med. 1974 Jun;67(6 Pt 1):473-6. doi: 10.1177/00359157740676P122.
7
Randomized clinical trials in breast cancer: a tabular summary. Part 1: Primary breast cancer.乳腺癌随机临床试验：表格总结。第1部分：原发性乳腺癌。
Arch Geschwulstforsch. 1986;56(3):211-36.
8
[Breast-preserving therapy of breast carcinoma].[乳腺癌的保乳治疗]
Dtsch Med Wochenschr. 1988 Oct 14;113(41):1601-3. doi: 10.1055/s-2008-1067857.
9
Treatment of breast cancer.乳腺癌的治疗。
Ann Chir Gynaecol. 2000;89(3):187-90.
10
Management of axillary disease.腋窝疾病的管理
Surg Oncol Clin N Am. 2014 Jul;23(3):473-86. doi: 10.1016/j.soc.2014.03.007. Epub 2014 Apr 13.
引用本文的文献
1
Trials and tribulations: thoughts on the organisation of multicentre clinical studies.艰难困苦：关于多中心临床研究组织的思考
Br Med J. 1980 Oct 4;281(6245):918-20. doi: 10.1136/bmj.281.6245.918.
2
The cancer research campaign (King's/Cambridge trial for early breast cancer: clinico-pathological aspects.癌症研究运动（国王学院/剑桥早期乳腺癌试验：临床病理方面）
Br J Cancer. 1982 May;45(5):655-69. doi: 10.1038/bjc.1982.106.
3
Annual review of surgery 1972.《1972年外科年鉴》
Postgrad Med J. 1973 Sep;49(575):644-55. doi: 10.1136/pgmj.49.575.644.
4
Immunotherapy in treatment of breast cancer.免疫疗法在乳腺癌治疗中的应用。
Proc R Soc Med. 1974 Apr;67(4):294-6.
5
Management of early cancer of the breast. Report on an international multicentre trial supported by the Cancer Research Campaign.早期乳腺癌的治疗。由癌症研究运动支持的一项国际多中心试验报告。
Br Med J. 1976 May 1;1(6017):1035-8. doi: 10.1136/bmj.1.6017.1035.
6
The role of local treatment for primary carcinoma of the breast.局部治疗在乳腺癌原发性癌中的作用。
Ann R Coll Surg Engl. 1978 Nov;60(6):479-82.
7
Prognostic value of serum levels of immunoglobulins (IgG, IgA, IgM and IgE) in breast cancer: a preliminary study.血清免疫球蛋白（IgG、IgA、IgM和IgE）水平在乳腺癌中的预后价值：一项初步研究。
Br J Cancer. 1977 Nov;36(5):550-7. doi: 10.1038/bjc.1977.230.
本文引用的文献
1
Results of simple mastectomy without irradiation in the treatment of operative stage I cancer of the breast.单纯乳房切除术而非放疗治疗手术一期乳腺癌的结果。
Ann Surg. 1968 Sep;168(3):330-6. doi: 10.1097/00000658-196809000-00003.
2
Reticulo-endothelial activity in humans with cancer.患癌人类的网状内皮系统活性
Br J Surg. 1970 Oct;57(10):748-52. doi: 10.1002/bjs.1800571013.
3
Immunological changes after radiotherapy for mammary carcinoma.乳腺癌放疗后的免疫学变化。
Ann Inst Pasteur (Paris). 1972 Apr;122(4):883-94.
4
Postoperative radiotherapy in the treatment of breast cancer: results of the NSABP clinical trial.乳腺癌治疗中的术后放疗：NSABP临床试验结果
Ann Surg. 1970 Oct;172(4):711-32. doi: 10.1097/00000658-197010000-00016.
5
The number of patients required in a clinical trial.一项临床试验所需的患者数量。
Br J Radiol. 1971 Feb;44(518):122-5. doi: 10.1259/0007-1285-44-518-122.
6
Cellular immunity against tumor antigens.针对肿瘤抗原的细胞免疫。
Adv Cancer Res. 1969;12:167-223. doi: 10.1016/s0065-230x(08)60331-0.
7
Treatment of early breast cancer: a report after ten years of a clinical trial.早期乳腺癌的治疗：一项临床试验十年后的报告
Br Med J. 1972 May 20;2(5811):423-9. doi: 10.1136/bmj.2.5811.423.
8
Lymphopenia and change in distribution of human B and T lymphocytes in peripheral blood induced by irradiation for mammary carcinoma.乳腺癌放疗所致外周血淋巴细胞减少及人B淋巴细胞和T淋巴细胞分布变化
Lancet. 1972 Jun 24;1(7765):1352-6. doi: 10.1016/s0140-6736(72)91091-4.
9
Management of early carcinoma of the breast.
Lancet. 1972 Jul 8;2(7767):85. doi: 10.1016/s0140-6736(72)91565-6.
10
Treatment of stage-II carcinoma of the female breast.
Lancet. 1971 Nov 13;2(7733):1086-7. doi: 10.1016/s0140-6736(71)90398-9.
Zotero 插件