噬菌体φX174 DNA在大肠杆菌C的温度敏感型dnaE突变体中的复制。
Replication of bacteriophage phiX174 DNA in a temperature-sensitive dnaE mutant of Escherichia coli C.
作者信息
Dumas L B, Miller C A
出版信息
J Virol. 1973 Jun;11(6):848-55. doi: 10.1128/JVI.11.6.848-855.1973.
Abstract
Bacteriophage phiX174 cannot grow in a temperature-sensitive dnaE (DNA polymerase III) mutant of Escherichia coli C at the nonpermissive temperature. The inability to grow is the result of inhibition of virus DNA synthesis. The synthesis of the parental replicative form is unaffected, but the replication of the replicative form and the synthesis of the single-stranded virus DNA are inhibited.
摘要
噬菌体φX174在非允许温度下不能在大肠杆菌C的温度敏感型dnaE（DNA聚合酶III）突变体中生长。无法生长是病毒DNA合成受到抑制的结果。亲本复制型的合成未受影响，但复制型的复制和单链病毒DNA的合成受到抑制。
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