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微生物细胞的自溶作用:金黄色葡萄球菌突变体中自溶酶的盐激活

Autolysis of microbial cells: salt activation of autolytic enzymes in a mutant of Staphylococcus aureus.

作者信息

Gilpin R W, Chatterjee A N, Young F E

出版信息

J Bacteriol. 1972 Jul;111(1):272-83. doi: 10.1128/jb.111.1.272-283.1972.

DOI:10.1128/jb.111.1.272-283.1972
PMID:4591480
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC251268/
Abstract

The effect of various salts on the autolysis of cell wall of a ribitol teichoic acid-deficient mutant of Staphylococcus aureus H (strain 52A5 carrying tar-1) was compared with the parent strain. In the presence of high concentrations of certain salts such as 1.0 m NaCl, the mutant undergoes autolysis with the release of osmotically sensitive spheroplasts. The parent strain is not affected by these conditions. The stimulation of lysis is related to an activation of N-acylmuramyl-l-alanine amidase.

摘要

将各种盐对金黄色葡萄球菌H的核糖醇磷壁酸缺陷型突变体(携带tar-1的菌株52A5)细胞壁自溶的影响与亲本菌株进行了比较。在高浓度的某些盐(如1.0 m NaCl)存在下,突变体发生自溶并释放出对渗透压敏感的原生质球。亲本菌株不受这些条件的影响。裂解的刺激与N-酰基胞壁酰-L-丙氨酸酰胺酶的激活有关。

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J Bacteriol. 1945 Aug;50(2):201-3.
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Temperature-Sensitive Osmotically Fragile Mutants of Staphylococcus aureus.金黄色葡萄球菌的温度敏感渗透脆性突变体
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A fractionation procedure for studies of the synthesis of cell-wall mucopeptide and of other polymers in cells of Staphylococcus aureus.一种用于研究金黄色葡萄球菌细胞中细胞壁粘肽及其他聚合物合成的分级分离程序。
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Front Microbiol. 2018 Oct 29;9:2575. doi: 10.3389/fmicb.2018.02575. eCollection 2018.
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ScientificWorldJournal. 2014 Jan 23;2014:908121. doi: 10.1155/2014/908121. eCollection 2014.
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