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[在“宇宙-690”生物卫星飞行影响下大鼠骨骼肌微粒体部分磷脂的含量和组成变化]

[Change in the content and makeup of the phospholipids in the microsomal fraction of rat skeletal muscles under the influence of a flight on the Kosmos-690 biosatellite].

作者信息

Belitskaia R A

出版信息

Kosm Biol Aviakosm Med. 1979 Jan-Feb;13(1):19-23.

PMID:423509
Abstract

The content and composition of phospholipids in the microsomes isolated from the back femoral muscles of rats flown for 20.5 days aboard the biosatellite Cosmos-690 were studied. Gamma-irradiation applied in the ground-based control experiments did not change the amount of total phospholipids in microsomes of skeletal muscles and altered insignificantly the content of their individual fractions. On the 2nd postflight day a substantial increase in the content of total and fractional phospholipids in microsomes was found. The decrease seems to be induced by weightlessness. On the 26th postflight day the content of total phospholipids returned to the normal whereas their fractional composition still remained changed.

摘要

对搭载生物卫星“宇宙-690号”飞行20.5天的大鼠股后肌分离出的微粒体中磷脂的含量和组成进行了研究。在地面对照实验中进行的γ射线照射并未改变骨骼肌微粒体中总磷脂的含量,其各个组分的含量变化也不显著。在飞行后第2天,发现微粒体中总磷脂和各组分磷脂的含量大幅增加。这种减少似乎是由失重引起的。在飞行后第26天,总磷脂含量恢复正常,但其组分组成仍有变化。

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