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[“宇宙-690”生物卫星飞行后大鼠骨骼肌混合纤维组织代谢]

[Skeletal muscle mixed fiber tissue metabolism in rats after a flight on the Kosmos-690 biosatellite].

作者信息

Gaevskaia M S, Belitskaia R A, Kolganova N S, Kolchina E V, Kurkina L M

出版信息

Kosm Biol Aviakosm Med. 1979 May-Jun;13(3):28-31.

PMID:449263
Abstract

On the R+O day the quadriceps muscle of rats showed a decrease in the content of T protein and an inhibition of LDH activity of sacroplasmatic proteins. These changes resulted from the combined affect of space flight factors and gamma-irradiation, and may be considered as a decline of compensatory synthetic processes responsible for the recovery of muscle proteins in weightlessness. Inhibition of the age-associated shift of the M:H ratio of LDH found on the R+25 day can be attributed to the inhibitory effect of gamma-irradiation. No change in the content of glycogen in the gastrocnemius muscle of flight rats was noted.

摘要

在“恢复+照射”日,大鼠股四头肌的T蛋白含量降低,肌浆蛋白的乳酸脱氢酶(LDH)活性受到抑制。这些变化是太空飞行因素和γ射线辐射共同作用的结果,可被视为负责肌肉蛋白在失重状态下恢复的代偿性合成过程的衰退。在“恢复+25”日发现的与年龄相关的LDH的M:H比值变化受到抑制,这可归因于γ射线辐射的抑制作用。未观察到飞行大鼠腓肠肌中糖原含量的变化。

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