细胞质膜在控制核信使核糖核酸运输及蛋白质合成起始过程中的作用。
The role of cytoplasmic membranes in controlling the transport of nuclear messenger RNA and initiation of protein synthesis.
作者信息
Shiokawa K, Pogo A O
出版信息
Proc Natl Acad Sci U S A. 1974 Jul;71(7):2658-62. doi: 10.1073/pnas.71.7.2658.
Abstract
Three different classes of poly(A)-containing RNA have been identified in the yeast system. They have been characterized by their kinetics of labeling, by their localization in the nuclear, membranous, and soluble cytoplasmic fractions, and by their size. The evidence indicates that the membrane-bound poly(A)-containing RNA is a product of the nuclear poly(A)-containing RNA and is the precursor of the polysomal poly(A)-containing RNA. In addition, it has been demonstrated that transport of mRNA is coupled with protein synthesis.
摘要
在酵母系统中已鉴定出三类不同的含聚腺苷酸（poly(A)）的RNA。它们通过标记动力学、在细胞核、膜和可溶性细胞质组分中的定位以及大小来表征。证据表明，膜结合的含poly(A)的RNA是细胞核中含poly(A)的RNA的产物，并且是多核糖体含poly(A)的RNA的前体。此外，已证明mRNA的转运与蛋白质合成相关联。
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