Kupersztoch-Portnoy Y M, Miklos G L, Helinski D R
J Bacteriol. 1974 Oct;120(1):545-8. doi: 10.1128/jb.120.1.545-548.1974.
The presence of supercoiled deoxyribonucleic acid in the form of a relaxation complex is described for the antibiotic resistance plasmids R64, R28K, and R6K. The properties of these relaxation complexes indicate that they consist of a covalently closed circular deoxyribonucleic acid molecule associated with an activable, single strand-specific endonuclease.
已描述了抗生素抗性质粒R64、R28K和R6K以松弛复合体形式存在的超螺旋脱氧核糖核酸。这些松弛复合体的特性表明它们由与一种可激活的单链特异性内切核酸酶相关联的共价闭合环状脱氧核糖核酸分子组成。