Pope J H, Morrison L, Moss D J, Parsons P G
Pathology. 1979 Apr;11(2):191-5. doi: 10.3109/00313027909061945.
A series of 10 cell lines established from human malignant melanomas is described. The morphology varied but, in general, was epithelioid. Five produced visible melanin in culture but others produced melanin precursors. All lines were aneuploid and each had a distinctive human karyotype. One line appeared not to have the same sex as the patient but its karyotype was distinct from that of other lines.
本文描述了从人类恶性黑色素瘤建立的一系列10个细胞系。其形态各异,但总体上为上皮样。5个细胞系在培养中产生可见黑色素,而其他细胞系产生黑色素前体。所有细胞系均为非整倍体,且每个细胞系都有独特的人类核型。有一个细胞系的性别似乎与患者不同,但其核型与其他细胞系不同。