大肠杆菌中核糖体蛋白基因表达的严格控制。
Stringent control of ribosomal protein gene expression in Escherichia coli.
作者信息
Dennis P P, Nomura M
出版信息
Proc Natl Acad Sci U S A. 1974 Oct;71(10):3819-23. doi: 10.1073/pnas.71.10.3819.
Abstract
The regulation of the expression of ribosomal protein genes was examined during partial inhibition of tRNA aminoacylation in isogenic rel(+) and rel(-) strains of E. coli B carrying a temperature-sensitive mutation in valyl-tRNA synthetase (EC 6.1.1.9) gene. Measurements of the differential synthesis rate of ribosomal protein, alpha(r) (ribosomal protein synthesis rate/total protein synthesis rate), indicate that ribosomal protein synthesis is regulated directly or indirectly by availability of charged tRNA, and that the synthesis of ribosomal protein, like the synthesis of rRNA, is subject to the influence of the rel gene control system.
摘要
在携带缬氨酰 - tRNA合成酶（EC 6.1.1.9）基因温度敏感突变的大肠杆菌B的同基因rel(+)和rel(-)菌株中，当tRNA氨酰化受到部分抑制时，对核糖体蛋白基因表达的调控进行了研究。核糖体蛋白α(r)（核糖体蛋白合成速率/总蛋白合成速率）差异合成速率的测量表明，核糖体蛋白的合成直接或间接受带电荷tRNA可用性的调节，并且核糖体蛋白的合成与rRNA的合成一样，受到rel基因控制系统的影响。
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本文引用的文献
1
FATE OF THE RIBOSOMAL RNA PRODUCED BY A "RELAXED" MUTANT OF ESCHERICHIA COLI.大肠杆菌“松弛”突变体产生的核糖体RNA的命运
J Mol Biol. 1964 Aug;9:472-88. doi: 10.1016/s0022-2836(64)80220-5.
2
A genetic locus for the regulation of ribonucleic acid synthesis.一个用于调节核糖核酸合成的基因位点。
Proc Natl Acad Sci U S A. 1961 Dec 15;47(12):2005-14. doi: 10.1073/pnas.47.12.2005.
3
Amino acid composition of ribosomes from Escherichia coli.大肠杆菌核糖体的氨基酸组成。
J Mol Biol. 1962 May;4:395-406. doi: 10.1016/s0022-2836(62)80020-5.
4
An improved method for thin-layer chromatography of nucleotide mixtures containing 32P-labelled orthophosphate.一种用于含32P标记正磷酸盐的核苷酸混合物的薄层色谱改进方法。
J Chromatogr. 1969 Mar 11;40(1):103-9. doi: 10.1016/s0021-9673(01)96624-5.
5
Synthesis and breakdown of proteins in Escherichia coli during amino-acid starvation.氨基酸饥饿期间大肠杆菌中蛋白质的合成与分解
J Mol Biol. 1971 Apr 14;57(1):35-57. doi: 10.1016/0022-2836(71)90118-5.
6
Ribosomal protein synthesis during amino acid starvation and chloramphenicol treatment.氨基酸饥饿和氯霉素处理期间的核糖体蛋白质合成。
J Mol Biol. 1970 Aug;51(3):491-9. doi: 10.1016/0022-2836(70)90003-3.
7
Ribosomal proteins. VII. Two-dimensional polyacrylamide gel electrophoresis for fingerprinting of ribosomal proteins.核糖体蛋白。VII. 用于核糖体蛋白指纹图谱分析的二维聚丙烯酰胺凝胶电泳
Anal Biochem. 1970 Aug;36(2):401-12. doi: 10.1016/0003-2697(70)90376-3.
8
Physiology and genetics of the "ribonucleic acid control" locus in escherichia coli.大肠杆菌中“核糖核酸控制”位点的生理学与遗传学
Bacteriol Rev. 1968 Sep;32(3):206-26. doi: 10.1128/br.32.3.206-226.1968.
9
Differential rate of ribosomal protein synthesis in Escherichia coli B/r.大肠杆菌B/r中核糖体蛋白合成的差异速率。
J Mol Biol. 1974 Apr 15;84(3):407-22. doi: 10.1016/0022-2836(74)90449-5.
10
Macromolecular composition during steady-state growth of Escherichia coli B-r.大肠杆菌B-r稳态生长过程中的大分子组成
J Bacteriol. 1974 Jul;119(1):270-81. doi: 10.1128/jb.119.1.270-281.1974.
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