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A simple procedure for localized mutagenesis using nitrosoguanidine.

作者信息

Oeschger M P, Berlyn M K

出版信息

Mol Gen Genet. 1974;134(1):77-83. doi: 10.1007/BF00332814.

DOI:10.1007/BF00332814
PMID:4617157
Abstract
摘要

相似文献

1
A simple procedure for localized mutagenesis using nitrosoguanidine.一种使用亚硝基胍进行定位诱变的简单方法。
Mol Gen Genet. 1974;134(1):77-83. doi: 10.1007/BF00332814.
2
Evidence that pretreatment of Escherichia coli cells with N-methyl-N'-nitro-N-nitrosoguanidine enhances mutability of subsequently infecting phage lambda.用N-甲基-N'-硝基-N-亚硝基胍预处理大肠杆菌细胞可增强随后感染的λ噬菌体的变异性的证据。
Mol Gen Genet. 1973 Nov 22;126(4):319-24. doi: 10.1007/BF00269441.
3
An Escherichia coli mutant refractory to nitrosoguanidine mutagenesis.一种对亚硝基胍诱变具有抗性的大肠杆菌突变体。
Mol Gen Genet. 1980;178(3):625-31. doi: 10.1007/BF00337870.
4
Mutagenic and prophage-inducing activities of 1-alkyl-3-nitro-1-nitrosoguanidines.1-烷基-3-硝基-1-亚硝基胍的诱变及原噬菌体诱导活性
Chem Pharm Bull (Tokyo). 1971 Sep;19(9):1914-8. doi: 10.1248/cpb.19.1914.
5
Environmental mutagen testing in Escherichia coli and phage lambda.大肠杆菌和λ噬菌体中的环境诱变剂检测
Mutat Res. 1974 Aug;26(4):235-41. doi: 10.1016/s0027-5107(74)80020-5.
6
Isolation and characterization of a temperature-sensitive amber suppressor mutant of Escherichia coli K12.大肠杆菌K12温度敏感型琥珀抑制突变体的分离与鉴定
Mol Gen Genet. 1973;123(1):77-88. doi: 10.1007/BF00282991.
7
[Genetic study of Mal mutants induced in Escherichia coli by nitrosoguanidine].[亚硝基胍诱导大肠杆菌中Mal突变体的遗传学研究]
Experientia. 1973 Nov 15;29(11):1429-30. doi: 10.1007/BF01922859.
8
Kinetics of the phenotypic expression of mutations for streptomycin resistance induced by methylmethane sulfonate, N-methyl-N'-nitro-N-nitrosoguanidine, and ultraviolet light in Escherichia coli K-12.甲磺酸甲酯、N-甲基-N'-硝基-N-亚硝基胍和紫外线在大肠杆菌K-12中诱导产生链霉素抗性突变的表型表达动力学。
Sov Genet. 1971 May;7(5):664-8.
9
Studies on the substrate specificity of the T 4 excision repair endonuclease.关于T4切除修复内切核酸酶底物特异性的研究。
Mutat Res. 1972 Jun;15(2):113-23. doi: 10.1016/0027-5107(72)90024-3.
10
Proflavin mutagenesis of bacteria.细菌的原黄素诱变
J Mol Biol. 1974 Oct 15;89(1):17-32. doi: 10.1016/0022-2836(74)90160-0.

引用本文的文献

1
Regulation of arsenate resistance in Desulfovibrio desulfuricans G20 by an arsRBCC operon and an arsC gene.由arsRBCC操纵子和arsC基因对脱硫脱硫弧菌G20中砷酸盐抗性的调控
J Bacteriol. 2007 May;189(10):3705-11. doi: 10.1128/JB.01913-06. Epub 2007 Mar 2.
2
Linkage map of Escherichia coli K-12, edition 6.大肠杆菌K-12连锁图谱，第6版。
Microbiol Rev. 1980 Mar;44(1):1-56. doi: 10.1128/mr.44.1.1-56.1980.
3
High efficiency temperature-sensitive amber suppressor strains of Escherichia coli K12: isolation of strains with suppressor-enhancing mutations.

本文引用的文献

1
Selecting bacterial mutants by the penicillin method.用青霉素法筛选细菌突变体。
Science. 1960 Feb 26;131(3400):604-5. doi: 10.1126/science.131.3400.604.
2
Acetylornithinase of Escherichia coli: partial purification and some properties.大肠杆菌的乙酰鸟氨酸酶：部分纯化及某些性质
J Biol Chem. 1956 Jan;218(1):97-106.
3
Localized mutagenesis of any specific small region of the bacterial chromosome.细菌染色体任何特定小区域的定位诱变。
大肠杆菌K12的高效温度敏感琥珀抑制菌株：具有抑制增强突变的菌株的分离
Mol Gen Genet. 1980;177(4):545-52. doi: 10.1007/BF00272662.
4
Production and characterization of streptomycin dependent mutants of Pasteurella multocida from bovine haemorrhagic septicaemia.牛出血性败血症多杀性巴氏杆菌链霉素依赖突变体的产生与特性研究
Can J Comp Med. 1980 Oct;44(4):418-22.
5
Adaptive response of Bacillus subtilis to N-methyl-N'-nitro-N-nitrosoguanidine.枯草芽孢杆菌对N-甲基-N'-硝基-N-亚硝基胍的适应性反应。
J Bacteriol. 1983 Feb;153(2):756-62. doi: 10.1128/jb.153.2.756-762.1983.
6
An amber mutation in the gene encoding the beta' subunit of Escherichia coli RNA polymerase.大肠杆菌RNA聚合酶β'亚基编码基因中的琥珀突变。
J Bacteriol. 1982 Nov;152(2):736-46. doi: 10.1128/jb.152.2.736-746.1982.
7
Cloning of the ugp region containing the structural genes for the pho regulon-dependent sn-glycerol-3-phosphate transport system of Escherichia coli.大肠杆菌中受pho调节子依赖的sn-甘油-3-磷酸转运系统结构基因所在的ugp区域的克隆。
Mol Gen Genet. 1983;192(1-2):177-86. doi: 10.1007/BF00327664.
8
Genetics of the glutamine transport system in Escherichia coli.大肠杆菌中谷氨酰胺转运系统的遗传学
J Bacteriol. 1981 Sep;147(3):805-19. doi: 10.1128/jb.147.3.805-819.1981.
9
A single point mutation results in a constitutively activated and feedback-resistant chorismate mutase of Saccharomyces cerevisiae.一个单点突变导致酿酒酵母中组成型激活且抗反馈调节的分支酸变位酶。
J Bacteriol. 1989 Mar;171(3):1245-53. doi: 10.1128/jb.171.3.1245-1253.1989.
10
Selection and properties of Escherichia coli mutants defective in the synthesis of cyclopropane fatty acids.环丙烷脂肪酸合成缺陷型大肠杆菌突变体的筛选与特性
J Bacteriol. 1976 Feb;125(2):518-23. doi: 10.1128/jb.125.2.518-523.1976.
Proc Natl Acad Sci U S A. 1971 Dec;68(12):3158-62. doi: 10.1073/pnas.68.12.3158.
4
On the process of cellular division in Escherichia coli. I. Asymmetrical cell division and production of deoxyribonucleic acid-less bacteria.关于大肠杆菌细胞分裂的过程。一、不对称细胞分裂及无脱氧核糖核酸细菌的产生
J Mol Biol. 1968 Jul 14;35(1):175-92. doi: 10.1016/s0022-2836(68)80046-4.
5
Induction of closely linked multiple mutations by nitrosoguanidine.亚硝基胍诱导紧密连锁的多重突变
Nat New Biol. 1971 Mar 24;230(12):122-5. doi: 10.1038/newbio230122a0.
6
Characterization of REP- mutants and their interaction with P2 phage.REP-突变体的表征及其与P2噬菌体的相互作用。
Virology. 1970 Jan;40(1):72-83. doi: 10.1016/0042-6822(70)90380-6.
7
Mutagenesis of the replication point by nitrosoguanidine: map and pattern of replication of the Escherichia coli chromosome.用亚硝基胍对复制起点进行诱变：大肠杆菌染色体的复制图谱和模式
J Mol Biol. 1968 May 14;33(3):705-19. doi: 10.1016/0022-2836(68)90315-x.
8
Growth of bacteriophage H on male and female strains of Escherichia coli.噬菌体H在大肠杆菌雄性和雌性菌株上的生长情况。
J Virol. 1973 Mar;11(3):460-3. doi: 10.1128/JVI.11.3.460-463.1973.
9
Close linkage of the genes serC (for phosphohydroxy pyruvate transaminase) and serS (for seryl-transfer ribonucleic acid synthetase) in Escherichia coli K-12.大肠杆菌K-12中serC基因（磷酸羟基丙酮酸转氨酶基因）与serS基因（丝氨酰转运核糖核酸合成酶基因）的紧密连锁。
J Bacteriol. 1973 Mar;113(3):1091-5. doi: 10.1128/jb.113.3.1091-1095.1973.
10
Rapid mapping of conditional and auxotrophic mutations in Escherichia coli K-12.大肠杆菌K-12中条件性突变和营养缺陷型突变的快速定位
J Bacteriol. 1973 Feb;113(2):798-812. doi: 10.1128/jb.113.2.798-812.1973.