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胸腺（T）淋巴细胞对抵抗李斯特菌病的需求。

Requirement of thymus (T) lymphocytes for resistance to listeriosis.

作者信息

Lane F C, Unanue E R

出版信息

J Exp Med. 1972 May 1;135(5):1104-12. doi: 10.1084/jem.135.5.1104.

DOI:10.1084/jem.135.5.1104
PMID:4623315
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2138983/
Abstract

Spleen cells of mice infected with Listeria monocytogenes were adoptively transferred to normal mice. Such lymphocytes conferred resistance to a lethal challenge with Listeria. Hyperimmunization of the donor reduces the number of cells necessary to transfer effective immunity. Such spleen cells if treated with anti-theta serum do not transfer resistance to Listeria. Hence, thymus (T) lymphocytes are involved in the resistance to infection with the facultative intracellular bacteria L. monocytogenes.

摘要

将感染单核细胞增生李斯特菌的小鼠的脾细胞过继转移到正常小鼠体内。这类淋巴细胞赋予了对李斯特菌致死性攻击的抵抗力。供体的超免疫可减少转移有效免疫力所需的细胞数量。这类脾细胞若用抗θ血清处理，则不会转移对李斯特菌的抵抗力。因此，胸腺（T）淋巴细胞参与了对兼性细胞内细菌单核细胞增生李斯特菌感染的抵抗力。

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Requirement of thymus (T) lymphocytes for resistance to listeriosis.胸腺（T）淋巴细胞对抵抗李斯特菌病的需求。
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2
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本文引用的文献

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Studies on the immunological response to foreign tumor transplants in the mouse. I. The role of lymph node cells in conferring immunity by adoptive transfer.小鼠对外来肿瘤移植免疫反应的研究。I. 淋巴结细胞在过继性转移赋予免疫中的作用。
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Specific in vitro cytotoxicity of thymus-derived lymphocytes sensitized to alloantigens.对同种异体抗原致敏的胸腺来源淋巴细胞的特异性体外细胞毒性。
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Cellular hypersensitivity.细胞超敏反应。
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