胸腺（T）淋巴细胞对抵抗李斯特菌病的需求。
Requirement of thymus (T) lymphocytes for resistance to listeriosis.
作者信息
Lane F C, Unanue E R
出版信息
J Exp Med. 1972 May 1;135(5):1104-12. doi: 10.1084/jem.135.5.1104.
Abstract
Spleen cells of mice infected with Listeria monocytogenes were adoptively transferred to normal mice. Such lymphocytes conferred resistance to a lethal challenge with Listeria. Hyperimmunization of the donor reduces the number of cells necessary to transfer effective immunity. Such spleen cells if treated with anti-theta serum do not transfer resistance to Listeria. Hence, thymus (T) lymphocytes are involved in the resistance to infection with the facultative intracellular bacteria L. monocytogenes.
摘要
将感染单核细胞增生李斯特菌的小鼠的脾细胞过继转移到正常小鼠体内。这类淋巴细胞赋予了对李斯特菌致死性攻击的抵抗力。供体的超免疫可减少转移有效免疫力所需的细胞数量。这类脾细胞若用抗θ血清处理，则不会转移对李斯特菌的抵抗力。因此，胸腺（T）淋巴细胞参与了对兼性细胞内细菌单核细胞增生李斯特菌感染的抵抗力。
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