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两种不常见的微生物,土曲霉和美丽梅奇酵母,与强直性脊柱炎的肺部疾病有关。

Two unusual organisms, Aspergillus terreus and Metschnikowia pulcherrima, associated with the lung disease of ankylosing spondylitis.

作者信息

Kennedy W P, Milne L J, Blyth W, Crompton G K

出版信息

Thorax. 1972 Sep;27(5):604-10. doi: 10.1136/thx.27.5.604.

Abstract

Two male patients with ankylosing spondylitis and upper lobe fibrosis and cavitation are described. A pneumonic disease in one was associated with mycological and serological evidence of infection with but no other aspergillus species. A large pulmonary mycetoma developed in the second patient and among a number of other fungal isolates was found the yeast The association of ankylosing spondylitis with bronchopulmonary aspergillosis is considered; is described for the first time as a human pulmonary pathogen, and the possible pathogenicity of in the debilitated human subject is discussed.

摘要

本文描述了两名患有强直性脊柱炎且伴有上叶纤维化和空洞形成的男性患者。其中一名患者的肺炎与真菌感染的真菌学和血清学证据相关,但未发现其他曲霉菌种。第二名患者出现了一个大的肺真菌球,在多种其他真菌分离物中发现了酵母。文中考虑了强直性脊柱炎与支气管肺曲霉菌病的关联;首次将其描述为人类肺部病原体,并讨论了其在虚弱人类受试者中的可能致病性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4719/470565/67f6a1734750/thorax00125-0093-a.jpg

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