Hyland C A, Mason E C, Harden P A, Shaw A E, Maurer D, Hope S L
Vox Sang. 1979;36(3):137-41. doi: 10.1111/j.1423-0410.1979.tb04414.x.
Radioimmunoassay (RIA) using Austria II (Abbott) was found to be more sensitive for the detection of HBsAg than the Hepanostika Micro-Elisa system (Organon Teknika), by a factor of 5- to 20-fold for subtype 'ad' (with one exception), and 2- to 5-fold for subtype 'ay'. The sensitivities of RIA and the enzyme-linked immunosorbent assay (Elisa) have also been evaluated in the screening of 178 selected serum samples contributed by 7 different laboratories. Of these, 149 were found to be positive for HBsAg by RIA, 142 were positive by Elisa and 36 were positive by CEP.
研究发现，使用奥地利II型试剂（雅培公司）的放射免疫测定法（RIA）在检测乙肝表面抗原（HBsAg）方面比赫帕诺斯塔卡微量酶联免疫吸附测定系统（奥加农公司）更为灵敏，对于“ad”亚型（有一个例外），其灵敏度高5至20倍，对于“ay”亚型，灵敏度高2至5倍。放射免疫测定法（RIA）和酶联免疫吸附测定法（ELISA）的灵敏度也在对7个不同实验室提供的178份选定血清样本的筛查中进行了评估。其中，149份样本经放射免疫测定法检测为乙肝表面抗原阳性，142份经酶联免疫吸附测定法检测为阳性，36份经对流免疫电泳检测为阳性。
