Kerr A A, McQuillin J, Downham M A, Gardner P S
Lancet. 1975 Feb 8;1(7902):291-5. doi: 10.1016/s0140-6736(75)91205-2.
Influenza-B virus was identified in 102 children admitted to hospital during two epidemics in 1973 and 1974, enzbling the symptomatology of infection with this virus to be assessed in detail for the first time. Abdominal pain, often severe enough to require differentiation from acute appendicitis, emerged as a dominant symptom, especially in older children. Respiratory symptoms were often insignificant, although the lower respiratory tract was sometimes involved. Other symptoms in some children included convulsions and acute myalgia. The immunofluorescent method of virus diagnosis was found to be reliable for influenza B, except in a few cases ehere nasopharyngeal secretions were scanty, giving 97-5 percent copositivity with standard isolation techniques. The rapid result provided by immunofluorescence was helpful in clinical diagnosis and management and also in the control of hospital cross-infection.
1973年和1974年两次流感流行期间，在102名住院儿童中发现了乙型流感病毒，这使得首次能够详细评估感染该病毒后的症状表现。腹痛成为主要症状，通常严重到需要与急性阑尾炎相鉴别，尤其是在大龄儿童中。呼吸道症状往往不明显，尽管有时下呼吸道会受到累及。一些儿童的其他症状包括惊厥和急性肌痛。除了少数鼻咽分泌物稀少的病例外，发现病毒诊断的免疫荧光法对乙型流感可靠，与标准分离技术的阳性符合率为97.5%。免疫荧光提供的快速结果有助于临床诊断和治疗，也有助于控制医院内交叉感染。
