Fernández P, Torres-Goitia J, Ferreiro M, Rizzardini M
Bol Med Hosp Infant Mex. 1979 Jul-Aug;36(4):605-10.
Twenty-three low birth weight infants were studied to establish the role that breast milk plays in the intestinal colonization of the preterm infant, and in the control of epidemic diarrhea due to enteropathogenic E. coli, in nurseries. Twelve of these case were fed breast milk in bottles, and eleven with "humanized" powder cow's milk (NAN M.R.). Bacteriologic studies of feces were performed daily during the first 18 days of life. In 5 cases given breast milk, and in 8 receiving cow's milk, Staphylococcus aureus was isolated. Enteropathogenic E. coli was found in 3 cases with breast milk and in 6 with cow's milk. The finding of other non-pathogenic strains, was similar for both groups, except in the case of Proteus, that was found in 10 cases with breast milk, and in only 3 cases with cow's milk. Breast milk was unable to avoid the colonization by E. coli and in one case, was unable to eradicate this germ. None of the cases fed breast milk had diarrhea, including the three cases with E. coli. In another group, 4 cases developed severe acute diarrhea, due to enteropathogenic E. coli followed by 2 deaths. The results seem to point out that although colonization by enteropathogenic strains of E. coli is not completely avoided, these strains do not cause disease when these infants are fed breast milk.
对23名低体重婴儿进行了研究，以确定母乳在早产儿肠道定植以及在托儿所控制由致病性大肠杆菌引起的流行性腹泻中所起的作用。其中12例病例用奶瓶喂母乳，11例用“人乳化”奶粉（NAN M.R.）喂养。在出生后的前18天每天对粪便进行细菌学研究。在5例喂母乳的病例和8例喂牛奶的病例中分离出了金黄色葡萄球菌。在3例喂母乳的病例和6例喂牛奶的病例中发现了致病性大肠杆菌。两组中其他非致病性菌株的发现情况相似，但变形杆菌除外，在10例喂母乳的病例中发现了变形杆菌，而在仅3例喂牛奶的病例中发现了变形杆菌。母乳未能避免大肠杆菌的定植，并且在1例病例中，未能根除这种细菌。所有喂母乳的病例均未发生腹泻，包括3例感染大肠杆菌的病例。在另一组中，4例因致病性大肠杆菌出现了严重的急性腹泻，随后有2例死亡。结果似乎表明，尽管未能完全避免致病性大肠杆菌菌株的定植，但当这些婴儿喂母乳时，这些菌株不会引发疾病。
