盐酸替洛隆：干扰素诱导与病毒防护之间缺乏相关性。
Tilorone hydrochloride: lack of correlation between interferon induction and viral protection.
作者信息
Giron D J, Schmidt J P, Pindak F F
出版信息
Antimicrob Agents Chemother. 1972 Jan;1(1):78-9. doi: 10.1128/AAC.1.1.78.
Abstract
The protection of mice against MM virus infection and the induction of circulating interferon by tilorone hydrochloride were determined. Whereas protection was evident with doses of 0.15 and 1.5 mg/kg, interferon was not detected with doses lower than 150 mg/kg. Protection was apparently not dependent on interferon induction.
摘要
测定了盐酸替洛隆对小鼠抗MM病毒感染的保护作用以及诱导循环干扰素的能力。剂量为0.15和1.5mg/kg时保护作用明显，而剂量低于150mg/kg时未检测到干扰素。保护作用显然不依赖于干扰素的诱导。
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