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对新城疫病毒诱导的循环干扰素具有定量效应的基因。

Gene with quantitative effect on circulating interferon induced by Newcastle disease virus.

作者信息

de Maeyer E, de Maeyer-Guignard J

出版信息

J Virol. 1969 May;3(5):506-12. doi: 10.1128/JVI.3.5.506-512.1969.

Abstract

Circulating interferon production, induced by Newcastle disease virus, is about seven times higher in C(57) Black mice than i Balb/c/Gif mice. A Mendelian analysis was carried out and circulating interferon production was measured in reciprocal F(1) hybrids, in the F(2) generation, in progeny of backcrosses of F(1) hybrids to either parent strain, and in second backcross progeny. The results indicate that a single, partly dominant, autosomal factor is responsible for the difference in circulating interferon production between both parent strains.

摘要

由新城疫病毒诱导产生的循环干扰素,在C(57)黑鼠体内的产量比在Balb/c/Gif鼠体内高约7倍。进行了孟德尔分析,并在正反交F(1)杂种、F(2)代、F(1)杂种与任一亲本品系回交的后代以及二次回交后代中测量了循环干扰素产量。结果表明,一个单一的、部分显性的常染色体因子导致了两个亲本品系在循环干扰素产量上的差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f9a/375801/3e9e842f0428/jvirol00305-0059-a.jpg

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