Bodner S J, Koenig M G, Treanor L L, Goodman J S
Antimicrob Agents Chemother. 1972 Aug;2(2):57-60. doi: 10.1128/AAC.2.2.57.
Seventy Bacteroides strains isolated from clinical materials were tested in vitro against nine antibiotics by means of modified disc diffusion and agar dilution tests. Correlating the agar dilution susceptibility with the concentrations achievable in serum for each drug tested, we found that at least 90% of the strains were susceptible to clindamycin, chloramphenicol, carbenicillin, and lincomycin. Only 40% were susceptible to tetracycline. Except for tetracycline and chloramphenicol, the disc diffusion technique exhibited inadequate predictive value in terms of "susceptibility" and "resistance" for the Bacteroides strains tested.
从临床材料中分离出的70株拟杆菌菌株,通过改良纸片扩散法和琼脂稀释法,在体外对9种抗生素进行了测试。将琼脂稀释法测得的药敏结果与每种受试药物在血清中可达到的浓度进行关联分析,我们发现至少90%的菌株对克林霉素、氯霉素、羧苄青霉素和林可霉素敏感。只有40%的菌株对四环素敏感。除四环素和氯霉素外,纸片扩散技术对于受试的拟杆菌菌株在“敏感”和“耐药”方面显示出不足的预测价值。