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关于新西兰小鼠腹膜巨噬细胞对金黄色葡萄球菌吞噬作用的体外研究。

In vitro studies on the phagocytosis of Staphylococcus aureus by peritoneal macrophages of New Zealand mice.

作者信息

Whaley K, Singh H

出版信息

Immunology. 1973 Jan;24(1):25-35.

PMID:4685371
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1422887/
Abstract

The ability of peritoneal macrophages from NZB, NZW and BWF1 mice to phagocytose and subsequently kill has been studied and compared to peritoneal macrophages from CBA, BALB/c and CHf mice. Phagocytic indices determined in young and old New Zealand mice did not differ from those of the control strains. The bactericidal activity of the peritoneal macrophages did not show any interstrain differences. Incorporation of serum from old and young NZB mice into the culture medium did not affect phagocytosis or the rate at which phagocytosed bacteria were killed. Studies performed in the absence of serum from the culture medium showed that probably both phagocytosis and bactericidal activity were unimpaired.

摘要

已对NZB、NZW和BWF1小鼠的腹膜巨噬细胞吞噬并随后杀死细菌的能力进行了研究,并与CBA、BALB/c和CHf小鼠的腹膜巨噬细胞进行了比较。在年轻和年老的新西兰小鼠中测定的吞噬指数与对照品系的无差异。腹膜巨噬细胞的杀菌活性未显示出任何品系间差异。将年轻和年老NZB小鼠的血清加入培养基中,并不影响吞噬作用或吞噬细菌的杀灭速率。在培养基中无血清的情况下进行的研究表明,吞噬作用和杀菌活性可能均未受损。

相似文献

1
In vitro studies on the phagocytosis of Staphylococcus aureus by peritoneal macrophages of New Zealand mice.关于新西兰小鼠腹膜巨噬细胞对金黄色葡萄球菌吞噬作用的体外研究。
Immunology. 1973 Jan;24(1):25-35.
2
Phagocytosis and intracellular killing of Staphylococcus aureus by normal mouse peritoneal macrophages.正常小鼠腹腔巨噬细胞对金黄色葡萄球菌的吞噬作用及细胞内杀伤
Infect Immun. 1975 Aug;12(2):346-52. doi: 10.1128/iai.12.2.346-352.1975.
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Syngeneic mixed lymphocyte reaction between thymocytes and peripheral lymphoid cells in mice: strain specificity and nature of the target cell.小鼠胸腺细胞与外周淋巴细胞之间的同基因混合淋巴细胞反应:品系特异性及靶细胞性质
J Immunol. 1973 Feb;110(2):376-83.
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Age-related changes in the concentration of transcobalamin II (TC II) in mouse peritoneal cells.
J Reticuloendothel Soc. 1981 Sep;30(3):183-9.
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The in vitro activity of peritoneal exudate cells of NZB-B1 and BALB-C mice following intraperitoneal injection of spleen cells from diseased and "healthy" NZB-B1 and from old and young BALB-C mice.在腹腔注射来自患病和“健康”的NZB - B1小鼠以及老年和幼年BALB - C小鼠的脾细胞后,NZB - B1和BALB - C小鼠腹腔渗出细胞的体外活性。
Br J Exp Pathol. 1973 Apr;54(2):123-34.
6
Peritoneal macrophage cytotoxicity induced by serum in vitro.血清体外诱导的腹膜巨噬细胞细胞毒性
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Clonal proliferation of peritoneal exudate cells from New Zealand black mice: age-related changes.
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The in vitro activity of peritoneal exudate cells from New Zealand black mice (NZB/B1) in the presence of I-125-BSA (bovine serum albumin).在存在碘-125标记的牛血清白蛋白(I-125-BSA)的情况下,新西兰黑鼠(NZB/B1)腹腔渗出细胞的体外活性。
Clin Exp Immunol. 1972 Oct;12(2):263-72.
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[Interferon activation of the production of a factor increasing the bactericidal properties of mouse macrophages].
Biull Eksp Biol Med. 1988 Apr;105(4):461-4.
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[Limits of the phagocytizing capability of macrophages].
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引用本文的文献

1
Proliferation and colony-forming ability of peritoneal exudate cells in liquid culture.液体培养中腹腔渗出细胞的增殖及集落形成能力
J Exp Med. 1975 May 1;141(5):1114-32. doi: 10.1084/jem.141.5.1114.

本文引用的文献

1
THE NATURAL HISTORY OF AUTOIMMUNE DISEASE IN NZB MICE. A COMPARISON WITH THE PATTERN OF HUMAN AUTOIMMUNE MANIFESTATIONS.新西兰黑鼠自身免疫性疾病的自然史。与人类自身免疫表现模式的比较。
Ann Intern Med. 1963 Sep;59:265-76. doi: 10.7326/0003-4819-59-3-265.
2
The fate of bacteria within phagocytic cells. I. The degradation of isotopically labeled bacteria by polymorphonuclear leucocytes and macrophages.吞噬细胞内细菌的命运。I. 多形核白细胞和巨噬细胞对同位素标记细菌的降解
J Exp Med. 1963 Jan 1;117(1):27-42. doi: 10.1084/jem.117.1.27.
3
Phagocytosis and intracellular fate of Pasteurella tularensis: in vitro effects of exudate stimulants and streptomycin on phagocytic cells.土拉弗朗西斯菌的吞噬作用及细胞内命运:渗出物刺激物和链霉素对吞噬细胞的体外影响
J Reticuloendothel Soc. 1967 Jan;4(1):10-23.
4
Auto-immune disease in NZB and NZB-NZW F1 mice. Natural history and pathology.NZB 及 NZB-NZW F1 小鼠的自身免疫性疾病。自然病史与病理学。
Arch Pathol. 1967 Jan;83(1):20-30.
5
Protection of phagocytized bacteria from the killing action of antibiotics.保护被吞噬的细菌免受抗生素的杀伤作用。
Nature. 1966 Jun 11;210(5041):1131-2. doi: 10.1038/2101131a0.
6
The natural history of the NZB/NZW F1 hybrid mouse: a laboratory model of systemic lupus erythematosus.NZB/NZW F1杂交小鼠的自然史:系统性红斑狼疮的实验室模型
Australas Ann Med. 1965 Aug;14(3):185-91. doi: 10.1111/imj.1965.14.3.185.
7
Increased 7S antibody response to sheep erythrocytes in the 2-month-old NZB mouse.2月龄新西兰黑小鼠对绵羊红细胞的7S抗体反应增强。
Clin Exp Immunol. 1969 Sep;5(3):251-63.
8
Response of NZB mice to foreign antigen and development of autoimmune disease.新西兰黑鼠对外源抗原的反应及自身免疫性疾病的发展。
J Reticuloendothel Soc. 1969 Feb;6(1):78-93.
9
Role of macrophages in the immune response.
Bull Soc Chim Biol (Paris). 1968 Sep 28;50(5):1113-28.
10
Immune response to a soluble protein antigen in NZB mice.NZB小鼠对可溶性蛋白质抗原的免疫反应。
Nature. 1968 Sep 21;219(5160):1276-7. doi: 10.1038/2191276a0.