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The in vitro activity of peritoneal exudate cells of NZB-B1 and BALB-C mice following intraperitoneal injection of spleen cells from diseased and "healthy" NZB-B1 and from old and young BALB-C mice.

作者信息

Thomas H I, Weir D M

出版信息

Br J Exp Pathol. 1973 Apr;54(2):123-34.

Abstract

Intraperitoneal injection of live spleen and lymph node cells from Coombs positive NZB/B1 mice induces an increase in the total number of peritoneal exudate cells (PE cells) and splenomegaly in recipient Coombs negative animals and Balb/c mice. The recipient's PE cells showed an increased uptake of I BSA and a decreased degradation of the BSA in culture. The possibility that the living spleen and lymph node cells elaborate a lymphocyte activation product that affects the activity of macrophages is discussed.

摘要

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本文引用的文献

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Clin Exp Immunol. 1967 Jul;2(4):427-43.
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Autoimmune reactions and virus-like particles in germ-free NZB mice.
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