Thomas H I, Weir D M
Br J Exp Pathol. 1973 Apr;54(2):123-34.
Intraperitoneal injection of live spleen and lymph node cells from Coombs positive NZB/B1 mice induces an increase in the total number of peritoneal exudate cells (PE cells) and splenomegaly in recipient Coombs negative animals and Balb/c mice. The recipient's PE cells showed an increased uptake of I BSA and a decreased degradation of the BSA in culture. The possibility that the living spleen and lymph node cells elaborate a lymphocyte activation product that affects the activity of macrophages is discussed.
给Coombs阳性的NZB/B1小鼠的活脾细胞和淋巴结细胞进行腹腔注射,会使接受注射的Coombs阴性动物和Balb/c小鼠的腹腔渗出细胞(PE细胞)总数增加,并出现脾肿大。受体的PE细胞在培养中显示出对I BSA摄取增加,而BSA降解减少。文中讨论了活脾细胞和淋巴结细胞产生一种影响巨噬细胞活性的淋巴细胞激活产物的可能性。