在存在碘-125标记的牛血清白蛋白（I-125-BSA）的情况下，新西兰黑鼠（NZB/B1）腹腔渗出细胞的体外活性。
The in vitro activity of peritoneal exudate cells from New Zealand black mice (NZB/B1) in the presence of I-125-BSA (bovine serum albumin).
作者信息
Thomas H I, Weir D M
出版信息
Clin Exp Immunol. 1972 Oct;12(2):263-72.
Abstract
Peritoneal exudate cells from old NZB/B1 mice were found to be more active in taking up I-labelled bovine serum albumin than similar cells from age matched BALB/c, C57B1 and CBA mice. The cells from both young and old NZB/B1 mice were markedly less able to degrade the ingested antigen than cells from the other strains. These observations are discussed in relation to the development of autoimmune phenomena in the NZB/B1 strain.
摘要
研究发现，老龄NZB/B1小鼠的腹腔渗出细胞摄取碘标记牛血清白蛋白的活性高于年龄匹配的BALB/c、C57B1和CBA小鼠的类似细胞。与其他品系的细胞相比，年轻和老龄NZB/B1小鼠的细胞降解摄入抗原的能力明显较低。结合NZB/B1品系自身免疫现象的发展对这些观察结果进行了讨论。
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