细胞松弛素B在体外对伤口边缘内皮细胞增殖的抑制作用。
Cytochalasin B inhibition of endothelial proliferation at wound edges in vitro.
作者信息
Selden S C, Schwartz S M
出版信息
J Cell Biol. 1979 May;81(2):348-54. doi: 10.1083/jcb.81.2.348.
Abstract
Cytochalasin B prevents both migration and wound-associated replication when applied to wounded monolayers of bovine endothelium in tissue culture. The normal low background rate of replication in undisturbed areas of the cultures is not inhibited by cytochalasin B. These results suggest that some form of movement may be required for initiation of wound-associated replication by endothelial cells.
摘要
当将细胞松弛素B应用于组织培养中受伤的牛内皮单层细胞时，它会阻止迁移和伤口相关的复制。细胞松弛素B不会抑制培养物未受干扰区域正常的低背景复制率。这些结果表明，内皮细胞启动伤口相关复制可能需要某种形式的运动。
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