碳水化合物限制对肥胖糖尿病患者的影响：血糖控制与体重减轻的关系。
Effect of carbohydrate restriction in obese diabetics: relationship of control to weight loss.
作者信息
Wall J R, Pyke D A, Oakley W G
出版信息
Br Med J. 1973 Mar 10;1(5853):577-8. doi: 10.1136/bmj.1.5853.577.
Two hundred newly diagnosed, fat diabetics were studied to determine whether control of the diabetes depended on loss of weight or on carbohydrate restriction alone. Satisfactory control was achieved by dietary treatment alone in 159 patients 30 required oral hypoglycaemic drugs and 11 were 18 of whom had actually gained weight. Of the remaining patients, 30 required oral hypoglycaemic drugs and 11 were still uncontrolled but not yet on other treatment.The mean initial excess weight of all 200 patients was 28%. Of those who remained uncontrolled on diet alone the mean initial excess weight (31%) was slightly but not significantly greater than that of those who were controlled (27%). Patients who were controlled lost slightly more weight than patients who were not, but their excess weight at the time of control was still 21%.We conclude that in 80% of obese diabetics control can be achieved by diet alone and that it is usually independent of weight loss.
对200名新诊断出的肥胖糖尿病患者进行了研究，以确定糖尿病的控制是取决于体重减轻还是仅取决于碳水化合物限制。仅通过饮食治疗，159名患者实现了满意的控制；30名患者需要口服降糖药，11名患者仍未得到控制，但尚未接受其他治疗，其中18名患者体重实际上有所增加。其余患者中，30名需要口服降糖药，11名仍未得到控制。所有200名患者的平均初始超重为28%。仅靠饮食仍未得到控制的患者，其平均初始超重（31%）略高于得到控制的患者（27%），但差异不显著。得到控制的患者比未得到控制的患者体重减轻得略多，但他们在控制时的超重仍为21%。我们得出结论，80%的肥胖糖尿病患者仅通过饮食就能实现控制，而且这通常与体重减轻无关。
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