Oli J M, Ikeakor I P
Hum Nutr Appl Nutr. 1984 Dec;38(6):479-86.
Over a 3-year period, 160 new, non-obese, non-insulin-dependent Nigerian diabetics were managed with high carbohydrate diets (250 g-300 g daily) and oral hypoglycaemic drugs. Fifty-three patients (33.1 per cent) achieved excellent control of their blood glucose (mean fasting blood glucose of 7.0 mmol/l or less); 38 patients (23.8 per cent) achieved good control of their blood glucose (mean fasting blood glucose of 7.0-8.0 mmol/l); and 42 patients (26.3 per cent) achieved fair control of their blood glucose (mean fasting blood, glucose of 8.0-9.0 mmol/l). A total of 133 patients (83.1 per cent) therefore achieved satisfactory control of their blood glucose with mean fasting blood glucose levels of 9.0 mmol/l or less. In Nigeria where the staple diets of the population are high in carbohydrate but low in protein and fat, the management of diabetes mellitus has many problems. To reduce carbohydrate and increase protein intake is often expensive, and increased fat intake is unpalatable. We conclude that despite a high carbohydrate diet, the majority of non-obese, non-insulin-dependent Nigerian diabetics can achieve good blood glucose control. The high carbohydrate diet may even be beneficial to the patients.
在3年期间,160名新诊断的、非肥胖、非胰岛素依赖型尼日利亚糖尿病患者采用高碳水化合物饮食(每日250克至300克)和口服降糖药进行治疗。53名患者(33.1%)血糖控制极佳(空腹血糖均值为7.0毫摩尔/升或更低);38名患者(23.8%)血糖控制良好(空腹血糖均值为7.0至8.0毫摩尔/升);42名患者(26.3%)血糖控制尚可(空腹血糖均值为8.0至9.0毫摩尔/升)。因此,共有133名患者(83.1%)空腹血糖均值在9.0毫摩尔/升或更低,血糖得到了满意控制。在尼日利亚,当地居民的主食碳水化合物含量高但蛋白质和脂肪含量低,糖尿病管理存在诸多问题。减少碳水化合物摄入并增加蛋白质摄入往往成本高昂,而增加脂肪摄入又不合口味。我们得出结论,尽管采用高碳水化合物饮食,但大多数非肥胖、非胰岛素依赖型尼日利亚糖尿病患者仍能实现良好的血糖控制。高碳水化合物饮食甚至可能对患者有益。