人体胆盐池大小的调节
Regulation of bile salt pool size in man.
作者信息
Low-Beer T S, Pomare E W
出版信息
Br Med J. 1973 May 12;2(5862):338-40. doi: 10.1136/bmj.2.5862.338.
Abstract
When the enterohepatic circulation is intact the size of the bile salt pool is largely determined by the frequency of its enterohepatic circulation. This hypothesis, derived from studies of cholate kinetics in coeliac, cholecystectomy, and gall stone patients, represents the simplest interpretation of the data. A corollary is that daily cholate secretion is likely to be normal in these conditions and that therefore the propensity of bile to form cholesterol gall stones is not likely to be directly related to bile salt pool size.
摘要
当肠肝循环完整时，胆盐池的大小在很大程度上由其肠肝循环的频率决定。这一假说源自对乳糜泻、胆囊切除和胆结石患者胆酸盐动力学的研究，是对这些数据最简单的解释。由此得出的一个推论是，在这些情况下，每日胆酸盐分泌可能是正常的，因此胆汁形成胆固醇胆结石的倾向不太可能与胆盐池大小直接相关。
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