威尔逊氏病还是慢性铜中毒？
Wilson's disease or chronic copper poisoning?
作者信息
Walker-Smith J, Blomfield J
出版信息
Arch Dis Child. 1973 Jun;48(6):476-9. doi: 10.1136/adc.48.6.476.
Abstract
The case history is given of a child who presented at 14 months with ascites and was found to have severe micronodular cirrhosis with biochemical evidence of Wilson's disease, but in view of the severity of the pathology and early age of presentation, the possibility of chronic copper poisoning was investigated. It was found that the child's drinking water was obtained from a bore via new copper pipes. The bore water had a H of 4·4 and after passage through copper pipes had a very high copper level of 675 μg/100 ml. He subsequently died from liver failure and at necropsy very high copper levels were found in his liver. The final diagnosis remains uncertain.
摘要
本文介绍了一名14个月大出现腹水的儿童病例，经检查发现患有严重的微小结节性肝硬化，并有威尔逊病的生化证据。但鉴于病理状况的严重性和发病年龄较小，对慢性铜中毒的可能性进行了调查。发现该儿童的饮用水取自通过新铜管的水井。井水的pH值为4.4，流经铜管后铜含量极高，达到675微克/100毫升。他随后死于肝功能衰竭，尸检时发现其肝脏中的铜含量非常高。最终诊断仍不确定。
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WILSON'S DISEASE.威尔逊氏病
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Potential hepatotoxicity of copper in recurrent hemodialysis.反复血液透析中铜的潜在肝毒性。
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10
Food-poisoning due to copper in the morning tea.早茶中的铜导致食物中毒。
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