亚氯酸盐氧化直链淀粉作为干扰素产生的佐剂。
Chlorite-oxidized amylose as an adjuvant for interferon production.
作者信息
Levy H B, Duenwald J, Buckler C E
出版信息
Infect Immun. 1973 Mar;7(3):457-60. doi: 10.1128/iai.7.3.457-460.1973.
Abstract
Chlorite-oxidized amylose (COAM), when given intraperitoneally to mice and to cats, increased the titer of serum interferon subsequently induced by polyinosinic.polycytidylic acid (In.Cn). Increases ranged from 6- to 100-fold. Maximal effect was observed when COAM was given 3 h prior to In.Cn. COAM given intravenously prior to Newcastle disease virus also significantly increased serum interferon titers.
摘要
当腹腔注射给予小鼠和猫时，亚氯酸盐氧化直链淀粉（COAM）会提高随后由聚肌苷酸-聚胞苷酸（In.Cn）诱导产生的血清干扰素效价。增幅在6至100倍之间。当在给予In.Cn前3小时给予COAM时，观察到最大效果。在新城疫病毒之前静脉注射COAM也显著提高了血清干扰素效价。
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引用本文的文献
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Infect Immun. 1975 Jan;11(1):129-36. doi: 10.1128/iai.11.1.129-136.1975.
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