多发性肌炎及其他疾病患者淋巴细胞对骨骼肌的敏感性。
Lymphocyte sensitivity to skeletal muscle in patients with polymyositis and other disorders.
作者信息
Esiri M M, MacLennan I C, Hazleman B L
出版信息
Clin Exp Immunol. 1973 May;14(1):25-35.
Abstract
The transformation response of peripheral blood lymphocytes to human muscle antigen has been studied in patients with polymyositis, polymyalgia rheumatica and rheumatoid arthritis. Lymphocytes from patients with polymyositis and polymyalgia rheumatica, but not rheumatoid arthritis, showed transformation responses significantly higher than those in control groups, and the highest responses were found in patients with evidence of the most active clinical disease at the time of testing. The significance of finding hypersensitivity to crude muscle antigen in both these conditions is discussed.
摘要
对多发性肌炎、风湿性多肌痛和类风湿性关节炎患者外周血淋巴细胞对人肌肉抗原的转化反应进行了研究。多发性肌炎和风湿性多肌痛患者的淋巴细胞（而非类风湿性关节炎患者的淋巴细胞）显示出转化反应显著高于对照组，且在检测时临床疾病最活跃的患者中发现了最高反应。讨论了在这两种情况下发现对粗制肌肉抗原过敏的意义。
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本文引用的文献
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