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左旋咪唑治疗周期性中性粒细胞减少症。

Levamisole in the treatment of cyclical neutropenia.

作者信息

Proctor S J, Reid M M, Low W T

出版信息

Postgrad Med J. 1979;55(642):279-81. doi: 10.1136/pgmj.55.642.279.

Abstract

A child with cyclical neutropenia was observed before and during treatment with levamisole. Marked clinical improvement occurred while on levamisole. Deterioration occurred after stopping treatment. The improvement was not associated with changes in the neutrophil or monocyte counts, nor did tests of phagocytic cell function convincingly demonstrate improvement while the child was on treatment.

摘要

一名周期性中性粒细胞减少症患儿在接受左旋咪唑治疗前及治疗期间接受了观察。在服用左旋咪唑期间,患儿出现了明显的临床改善。停药后病情恶化。这种改善与中性粒细胞或单核细胞计数的变化无关,而且在患儿接受治疗期间,吞噬细胞功能测试也未令人信服地证明有改善。

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本文引用的文献

6
Letter: Levamisole and agranulocytosis.信函:左旋咪唑与粒细胞缺乏症。
Lancet. 1976 May 15;1(7968):1080-1. doi: 10.1016/s0140-6736(76)92261-3.
7
Immunostimulant therapy with levamisole for rheumatoid arthritis.
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Levamisole in prevention of recurrent upper-respiratory-tract infections in children.
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