Reid M M, Craft A W, Todd J A
Arch Dis Child. 1977 Mar;52(3):245-7. doi: 10.1136/adc.52.3.245.
Serial studies of numbers of circulating T and B lymphocytes at monthly intervals in children with acute lymphoblastic leukaemia showed a marked fall in the number of B cells, relatively greater than that of T cells, early in the course of maintenance chemotherapy and immediately after a course of cranial irradiation. The fall in the number of B cell is not a consequence of long-term chemotherapy, and is possibly related to a specific event such as cranial irradiation.
对急性淋巴细胞白血病患儿每月进行的循环T和B淋巴细胞数量的系列研究表明,在维持化疗早期及一轮头颅放疗后,B细胞数量显著下降,相对T细胞数量下降更明显。B细胞数量下降并非长期化疗的结果,可能与头颅放疗等特定事件有关。