离体牛肠系膜淋巴管的自发活动
Spontaneous activity in isolated bovine mesenteric lymphatics.
作者信息
Mawhinney H J, Roddie I C
出版信息
J Physiol. 1973 Mar;229(2):339-48. doi: 10.1113/jphysiol.1973.sp010141.
Abstract
- Longitudinal tension was measured in isolated segments (approximately 20 mm in length and 2 mm in diameter) of bovine mesenteric lymphatic vessels.2. Seventeen out of thirty-nine vessels showed regular spontaneous rhythmic contractions, the most common frequency being about 2/min.3. The strength of each contraction was related to the duration of the preceding pause, a longer pause being associated with a stronger contraction.4. Noradrenaline increased the frequency and decreased the amplitude of the contractions. This effect was abolished by alpha-receptor blockade with phentolamine.5. Isoprenaline slowed the frequency of the contractions. This effect was abolished by beta-receptor blockade with propranolol.6. Acetylcholine had little effect on the rate of spontaneous contractions.
摘要
对牛肠系膜淋巴管的离体节段（长度约20毫米，直径2毫米）测量纵向张力。
39条血管中有17条呈现规律的自发性节律性收缩，最常见的频率约为每分钟2次。
每次收缩的强度与前一次舒张期的时长有关，舒张期越长，收缩越强。
去甲肾上腺素增加收缩频率并减小收缩幅度。酚妥拉明阻断α受体后，此效应消失。
异丙肾上腺素减慢收缩频率。普萘洛尔阻断β受体后，此效应消失。
乙酰胆碱对自发性收缩频率影响很小。
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