尿毒症患者的皮肤试验敏感性及抗原诱导的淋巴细胞转化
Skin test sensitivity and antigen-induced lymphocyte transformation in uraemia.
作者信息
Selroos O, Pasternack A, Virolainen M
出版信息
Clin Exp Immunol. 1973 Jul;14(3):365-70.
Abstract
Serial tuberculin skin tests with 0·1–100 TU of PPD were performed on 209 patients with chronic renal disease. Skin test reactivity decreased with the severity of uraemia. Lymphocytes from three out of four skin test negative patients showed a high PPD-induced blast response . Thus, the absence of skin reactivity in uraemia does not always depend on a lack of antigen-sensitive lymphocytes.
摘要
对209例慢性肾病患者进行了0.1 - 100结核菌素单位（TU）的结核菌素皮肤试验。皮肤试验反应性随尿毒症严重程度降低。4例皮肤试验阴性患者中有3例的淋巴细胞显示出对结核菌素纯蛋白衍生物（PPD）诱导的母细胞化反应较高。因此，尿毒症患者皮肤无反应性并不总是取决于缺乏抗原敏感淋巴细胞。
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