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Experimental hepatic necrosis: studies on coagulation abnormalities, plasma clearance, and organ distribution of 125I-labelled fibrinogen.

作者信息

Rake M O, Flute P T, Pannell G, Shilkin K B, Williams R

出版信息

Gut. 1973 Jul;14(7):574-80. doi: 10.1136/gut.14.7.574.

DOI:10.1136/gut.14.7.574
PMID:4729927
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1412798/
Abstract

Studies in the rat with hepatic necrosis induced by carbon tetrachloride showed that the abnormalities in one-stage coagulation tests and the increased catabolism of fibrinogen were similar to those found in man with acute viral or drug-induced hepatic necrosis. Determination of the distribution of the radioactive label shows that excessive deposition was maximal in the liver but also occurred in the spleen. The appearance is delayed by heparin but accelerated by tranexamic acid.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dccf/1412798/475b8ec6f8ba/gut00632-0074-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dccf/1412798/e1f1676cd25d/gut00632-0074-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dccf/1412798/475b8ec6f8ba/gut00632-0074-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dccf/1412798/e1f1676cd25d/gut00632-0074-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dccf/1412798/475b8ec6f8ba/gut00632-0074-b.jpg

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Role of hemostatic factors in hepatic injury and disease: animal models de-liver.止血因子在肝损伤和疾病中的作用：动物模型研究。 （你提供的原文似乎不太完整或有拼写错误，推测可能是“Role of hemostatic factors in hepatic injury and disease: animal models deliver.”这样更通顺些，但我按照你给的原文进行了翻译）

本文引用的文献

1
The effect of diet and 1,1,1-trichloro-2,2-bis-(p-chlorophenyl)ethane (DDT) on microsomal hydroxylating enzymes and on sensitivity of rats to carbon tetrachloride poisoning.饮食和 1,1,1-三氯-2,2-双（对氯苯基）乙烷（DDT）对微粒体羟化酶的影响以及对大鼠四氯化碳中毒敏感性的影响。
Biochem J. 1966 Aug;100(2):564-71. doi: 10.1042/bj1000564.
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IN VIVO BEHAVIOR OF I-FIBRINOGEN.体内I型纤维蛋白原的行为
J Clin Invest. 1963 Mar;42(3):346-61. doi: 10.1172/JCI104721.
3
JAUNDICE AND ITS RELATION TO THERAPEUTIC AGENTS.黄疸及其与治疗药物的关系。
J Thromb Haemost. 2016 Jul;14(7):1337-49. doi: 10.1111/jth.13327. Epub 2016 May 10.
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Intravascular coagulation in acute liver failure in rats and its treatment with antithrombin III.
Gut. 1988 Aug;29(8):1103-8. doi: 10.1136/gut.29.8.1103.
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Early changes in coagulation following a paracetamol overdose and a controlled trial of fresh frozen plasma therapy.对乙酰氨基酚过量服用后凝血的早期变化及新鲜冰冻血浆治疗的对照试验
Gut. 1975 Aug;16(8):617-20. doi: 10.1136/gut.16.8.617.
6
Behaviour of 125I-fibrinogen and 131I-albumin in experimental galactosamine-induced hepatitis.125I-纤维蛋白原和131I-白蛋白在实验性半乳糖胺诱导的肝炎中的行为
Gut. 1977 Jul;18(7):547-55. doi: 10.1136/gut.18.7.547.
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Fibrin formation during asanguinous normothermic perfusion of the isolated rat liver.离体大鼠肝脏无血常温灌注期间的纤维蛋白形成
World J Surg. 1978 Mar;2(2):261-70. doi: 10.1007/BF01553569.
Lancet. 1965 Jan 23;1(7378):175-9. doi: 10.1016/s0140-6736(65)90969-4.
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Hemostatic mechanisms in liver disease.
Med Clin North Am. 1963 May;47:721-36. doi: 10.1016/s0025-7125(16)33574-x.
5
An electron microscopic study of thrombin-induced disseminated intravascular coagulation.
Blood. 1967 Feb;29(2):169-81.
6
Coagulation factors in chronic liver disease.慢性肝病中的凝血因子。
J Clin Pathol. 1969 Mar;22(2):199-204. doi: 10.1136/jcp.22.2.199.
7
Iodine-labelled fibrinogen: a review.
Br J Haematol. 1971 Jun;20(6):649-63. doi: 10.1111/j.1365-2141.1971.tb00804.x.
8
Intravascular coagulation in acute hepatic necrosis.急性肝坏死中的血管内凝血。
Lancet. 1970 Mar 14;1(7646):533-7. doi: 10.1016/s0140-6736(70)90767-1.
9
Early and intensive therapy of intravascular coagulation in acute liver failure.急性肝衰竭中血管内凝血的早期强化治疗
Lancet. 1971 Dec 4;2(7736):1215-8. doi: 10.1016/s0140-6736(71)90540-x.