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生殖道支原体感染。宫内感染:胎儿及胎盘的病理学研究。

Genital mycoplasma infection. Intrauterine infection: pathologic study of the fetus and placenta.

作者信息

Dische M R, Quinn P A, Czegledy-Nagy E, Sturgess J M

出版信息

Am J Clin Pathol. 1979 Aug;72(2):167-74. doi: 10.1093/ajcp/72.2.167.

DOI:10.1093/ajcp/72.2.167
PMID:474493
Abstract

Mycoplasma infection was present in the fetuses from three spontaneous abortions and in one second-trimester newborn. Gross examination revealed in most cases a severely infected placenta and membranes, with a fetus of normal appearance. The fetal infection presumably followed placental involvement and appeared to have been acquired shortly prior to delivery. Genital mycoplasmas, Ureaplasma urealyticum or Mycoplasma hominis, were isolated from the placentas and the fetal tissues, and from the genital tracts of the mothers. Isolation of mycoplasmas from the liver indicated that bloodstream dissemination of these organisms occurred in the fetus. In the fetus, the pathologic changes were variable. Lesions were identified in the lung by scanning electron microscopy of the bronchial tree in two cases and were accompanied by interstitial pneumonia. An abnormally dilated left ventricle suggestive of cardiomyopathy was observed in one case.

摘要

在三例自然流产胎儿及一例孕中期新生儿中发现支原体感染。大体检查显示,多数情况下胎盘和胎膜严重感染,而胎儿外观正常。胎儿感染推测是胎盘受累后发生的,且似乎是在分娩前不久获得的。从胎盘、胎儿组织以及母亲的生殖道中分离出了生殖支原体、解脲脲原体或人型支原体。从肝脏中分离出支原体表明这些微生物在胎儿体内发生了血行播散。在胎儿中,病理变化各不相同。通过对两例支气管树进行扫描电子显微镜检查,在肺中发现了病变,并伴有间质性肺炎。在一例中观察到左心室异常扩张,提示存在心肌病。

相似文献

1
Genital mycoplasma infection. Intrauterine infection: pathologic study of the fetus and placenta.生殖道支原体感染。宫内感染:胎儿及胎盘的病理学研究。
Am J Clin Pathol. 1979 Aug;72(2):167-74. doi: 10.1093/ajcp/72.2.167.
2
Placental infection with Mycoplasma homonis and Ureaplasma urealyticum: clinical correlation.人型支原体和解脲脲原体的胎盘感染:临床相关性
Obstet Gynecol. 1980 Oct;56(4):475-81.
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Chorioamnionitis and colonization of the newborn infant with genital mycoplasmas.绒毛膜羊膜炎与新生儿生殖器支原体定植
N Engl J Med. 1975 Jul 3;293(1):5-8. doi: 10.1056/NEJM197507032930102.
4
[Role of mycoplasmas in the last month of pregnancy and postpartum pathology. Prospective study of 577 pregnancies].[支原体在妊娠最后一个月及产后病理中的作用。对577例妊娠的前瞻性研究]
Rev Fr Gynecol Obstet. 1992 Mar;87(3):135-44.
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[Mycoplasma placentitis].[胎盘支原体炎]
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Isolation of Mycoplasma hominis and Ureaplasma urealyticum from amniotic fluid at 16-20 weeks of gestation: potential effect on outcome of pregnancy.妊娠16 - 20周时从羊水分离人型支原体和解脲脲原体:对妊娠结局的潜在影响。
Sex Transm Dis. 1983 Oct-Dec;10(4 Suppl):294-302.
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Diagnosis of genital Mycoplasma and Ureaplasma infections.生殖支原体和脲原体感染的诊断
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Histologic manifestations of perinatal genital mycoplasmal infection.围生期生殖道支原体感染的组织学表现。
Arch Pathol Lab Med. 1989 May;113(5):465-9.
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Isolation of genital mycoplasmas and Chlamydia trachomatis in stillborn and neonatal autopsy material.死产儿及新生儿尸检材料中生殖支原体和沙眼衣原体的分离
Arch Pathol Lab Med. 1988 Jul;112(7):749-51.
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Genital mycoplasmal infections: their relation to prematurity and other abnormalities of reproduction.生殖道支原体感染:它们与早产及其他生殖异常的关系。
J Clin Pathol Suppl (R Coll Pathol). 1976;10:95-8.

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Arch Gynecol Obstet. 1993;253(4):215-8. doi: 10.1007/BF02766648.
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Serotyping of Ureaplasma urealyticum by immunoperoxidase assay.通过免疫过氧化物酶测定法对解脲脲原体进行血清分型。
J Clin Microbiol. 1981 Apr;13(4):670-6. doi: 10.1128/jcm.13.4.670-676.1981.
7
Serological evidence of Ureaplasma urealyticum infection in neonatal respiratory disease.新生儿呼吸道疾病中解脲脲原体感染的血清学证据。
Yale J Biol Med. 1983 Sep-Dec;56(5-6):565-72.
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Mycoplasma hominis - a neglected human pathogen.人型支原体——一种被忽视的人类病原体。
Eur J Clin Microbiol. 1983 Aug;2(4):303-8. doi: 10.1007/BF02019458.
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Enzyme-linked immunosorbent assay for detection of specific antibodies to Ureaplasma urealyticum serotypes.用于检测解脲脲原体血清型特异性抗体的酶联免疫吸附测定
J Clin Microbiol. 1984 Mar;19(3):421-6. doi: 10.1128/jcm.19.3.421-426.1984.
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Chronic placentitis--a clinicopathological study.慢性胎盘炎——一项临床病理学研究。
Arch Gynecol. 1985;237(1):19-25. doi: 10.1007/BF02133947.