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1950年父母与1970年其子女的血压、总胆固醇及吸烟情况比较。

A comparison of blood pressure, total cholesterol and cigarette smoking in parents in 1950 and their children in 1970.

作者信息

Feinleib M, Garrison R J, Stallones L, Kannel W B, Castelli W P, McNamara P M

出版信息

Am J Epidemiol. 1979 Sep;110(3):291-303. doi: 10.1093/oxfordjournals.aje.a112814.

Abstract

Blood pressure and serum cholesterol levels as well as cigarette smoking are compared for parents who were examined in the Framingham Heart Study between 1948 and 1950 and their offspring who were studied in the early 1970s in the Framingham Offspring Study. For ages 30-49 years there are modest but significant differences in both systolic and diastolic blood pressure when mothers are compared to daughters, with the average pressures in the daughters being lower. Blood pressure differences in fathers and sons are not as large, and they disappear when families which include hypertensives are eliminated from the analysis. Total cholesterol levels were found to be significantly lower in both daughters and sons, but the difference was not large after adjusting for changes in methodology. The proportion of cigarette smokers was found to be substantially lower in the sons in all age groups, and modest reductions in cigarette smoking were also noted in all but the oldest (age 45--49 years) group of daughters.

摘要

对在1948年至1950年参加弗雷明汉心脏研究的父母及其在20世纪70年代初参加弗雷明汉子代研究的子代的血压、血清胆固醇水平以及吸烟情况进行了比较。在30至49岁年龄段,母亲与女儿相比,收缩压和舒张压均存在适度但显著的差异,女儿的平均血压较低。父亲与儿子之间的血压差异没有那么大,并且在分析中剔除包括高血压患者的家庭后,这种差异消失了。研究发现,女儿和儿子的总胆固醇水平均显著较低,但在对方法学变化进行调整后,差异不大。所有年龄组的儿子中吸烟者的比例均显著较低,除最年长(45 - 49岁)的女儿组外,其他女儿组的吸烟率也有适度下降。

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