Gianotti F
Arch Dis Child. 1973 Oct;48(10):794-9. doi: 10.1136/adc.48.10.794.
Papular acrodermatitis (PAC) is a fairly widespread, probably slightly infectious, nonrelapsing disease of childhood characterized by (a) papular eruption on the face and limbs lasting 20 days or more, (b) reactive reticulohistiocytic lymphadenitis, and (c) acute hepatitis, usually anicteric, which commonly lasts about 2 months. Australia antigen is always present; it is detectable 10 or more days after the onset of the skin eruption and persists from 2 months to several years. The mother of some children with PAC are found to be carriers of Au antigen, as are some sibs when tested many years later. Whether the causative agent of PAC is the same as that causing serum hepatitis, or is different, remains to be established.
丘疹性肢端皮炎（PAC）是一种较为常见的、可能具有轻微传染性的儿童非复发性疾病，其特征为：（a）面部和四肢出现丘疹性皮疹，持续20天或更长时间；（b）反应性网状组织细胞性淋巴结炎；（c）急性肝炎，通常无黄疸，通常持续约2个月。澳大利亚抗原总是存在；在皮疹发作后10天或更长时间可检测到，持续2个月至数年。一些患PAC儿童的母亲被发现是澳抗携带者，一些同胞在多年后检测时也是如此。PAC的病原体与引起血清性肝炎的病原体是否相同，或是否不同，仍有待确定。
