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碳酸酐酶抑制剂对正常血压和青光眼比格犬的眼压降低作用。

Ocular hypotensive effects of carbonic anhydrase inhibitors in normotensive and glaucomatous Beagles.

作者信息

Gelatt K N, Gum G, Williams L W, Gwin R M

出版信息

Am J Vet Res. 1979 Mar;40(3):334-45.

PMID:475084
Abstract

Four carbonic anhydrase inhibitors (acetazolamide, dichlorphenamide, ethoxzolamide, and methazolamide) cause ocular hypotony in normotensive and glaucomatous Beagles. Four dosages of acetazolamide and methazolamide and three dosages of dichlorphenamide and ethoxzolamide were evaluated. The extent of ocular hypotony after these carbonic anhydrase inhibitors was usually greater in glaucomatous Beagles than it was in normotensive Beagles.

摘要

四种碳酸酐酶抑制剂(乙酰唑胺、二氯苯磺胺、乙氧唑胺和甲醋唑胺)可使血压正常和患有青光眼的比格犬眼压降低。对乙酰唑胺和甲醋唑胺的四种剂量以及二氯苯磺胺和乙氧唑胺的三种剂量进行了评估。这些碳酸酐酶抑制剂给药后,青光眼比格犬的眼压降低程度通常大于血压正常的比格犬。

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Ocular hypotensive effects of carbonic anhydrase inhibitors in normotensive and glaucomatous Beagles.碳酸酐酶抑制剂对正常血压和青光眼比格犬的眼压降低作用。
Am J Vet Res. 1979 Mar;40(3):334-45.
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Evaluation of a topically administered carbonic anhydrase inhibitor (MK-927) in normotensive and glaucomatous beagles.局部应用碳酸酐酶抑制剂(MK - 927)对正常血压和青光眼比格犬的评估。
Am J Vet Res. 1991 Dec;52(12):2067-70.
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A comparison between the effect of topical and systemic carbonic anhydrase inhibitors on aqueous humor secretion.局部和全身碳酸酐酶抑制剂对房水分泌影响的比较。
Exp Eye Res. 1993 Jul;57(1):67-78. doi: 10.1006/exer.1993.1100.
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Effects of topical 1-epinephrine and dipivalyl epinephrine on intraocular pressure and pupil size in the normotensive and glaucomatous Beagle.局部应用1-肾上腺素和二特戊酰肾上腺素对正常血压和青光眼比格犬眼压及瞳孔大小的影响。
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Patient tolerance to carbonic anhydrase inhibitors.患者对碳酸酐酶抑制剂的耐受性。
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Changes in intraocular pressure associated with topical dorzolamide and oral methazolamide in glaucomatous dogs.青光眼犬局部应用多佐胺和口服醋甲唑胺相关的眼压变化
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[Effect of methazolamide on the intraocular pressure of patients with open-angle glaucoma (author's transl)].醋甲唑胺对开角型青光眼患者眼压的影响(作者译)
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Acetazolamide-like carbonic anhydrase inhibitors with topical ocular hypotensive activity.具有局部眼降压活性的乙酰唑胺样碳酸酐酶抑制剂。
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The pharmacology of methazolamide in relation to the treatment of glaucoma.
Invest Ophthalmol Vis Sci. 1977 Aug;16(8):730-42.
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Mol Pharmacol. 1967 Mar;3(2):204-15.

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