钙化性胰腺炎中的血清免疫球蛋白
Serum immunoglobulins in calcific pancreatitis.
作者信息
Bank S, Novis B H, Petersen E, Dowdle E, Marks I N
出版信息
Gut. 1973 Sep;14(9):723-5. doi: 10.1136/gut.14.9.723.
Abstract
Serum immunoglobulin concentrations were measured in 40 patients with calcific pancreatitis. A significant elevation of the mean serum IgA and IgG concentration when compared with a control group was found. The IgA was raised in 50% and the IgG in 27.5% when the individual results were assessed. The IgA did not appear to be of the secretory type. The possible significance of the raised IgA and IgG is discussed with reference to local pancreatic IgA production, autoimmune factors in chronic pancreatitis, and the ductal protein plugs in this disease.
摘要
对40例钙化性胰腺炎患者的血清免疫球蛋白浓度进行了测定。结果发现，与对照组相比，平均血清IgA和IgG浓度显著升高。在评估个体结果时，IgA升高的患者占50%，IgG升高的患者占27.5%。IgA似乎不是分泌型。本文参照胰腺局部IgA产生、慢性胰腺炎中的自身免疫因素以及该疾病中的导管蛋白栓，讨论了IgA和IgG升高的可能意义。
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