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本文引用的文献

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Corneal ulcer due to Candida parapsilosis (C. parakrusei).近平滑念珠菌(近平滑克鲁斯念珠菌)所致角膜溃疡
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Soil as natural reservoir for human pathogenic fungi.土壤作为人类致病真菌的天然储存库。
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Pathogenesis of Candida albicans infection following antibiotic therapy. III. The effect of antibiotics on the incidence of Candida albicans in the intestinal tract of mice.抗生素治疗后白色念珠菌感染的发病机制。III. 抗生素对小鼠肠道中白色念珠菌发生率的影响。
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The significance of saprophytism in the epidemiology of the mycoses.腐生现象在真菌病流行病学中的意义。
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[Determination of Candida; study of morphologic and physiologic characters of 78 strains isolated from pathologic material].[念珠菌的鉴定;对从病理材料中分离出的78株菌株的形态学和生理学特征的研究]
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The external surface of the human body as a habitat for nonfermenting nonpigmented yeasts.作为非发酵非色素沉着酵母栖息地的人体外表面。
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The effect of aureomycin and chloramphenicol on the fungal and bacterial flora of children.金霉素和氯霉素对儿童真菌和细菌菌群的影响。
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Microbiological problems of manned space flight.
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阿波罗宇航员真菌自发菌群的变化。

Changes in the fungal autoflora of Apollo astronauts.

作者信息

Taylor G R, Henney M R, Ellis W L

出版信息

Appl Microbiol. 1973 Nov;26(5):804-13. doi: 10.1128/am.26.5.804-813.1973.

DOI:10.1128/am.26.5.804-813.1973
PMID:4762399
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC379905/
Abstract

Specimens were repeatedly obtained for mycological examination from the skin, throat, urine, and feces of the six astronauts who conducted the Apollo 14 and Apollo 15 lunar exploration missions. Analysis of preflight data demonstrates that the process of severely restricting opportunities from colonization for 3 weeks before flight resulted in a 50% reduction in the number of isolated species. Postflight data indicate that exposure to the space flight environment for up to 2 weeks resulted in an even greater reduction with a relative increase in the potential pathogen Candida albicans. No incidences of microbial shock were observed when crewmembers were quarantined for 16 days after completion of the space flight. Intercrew transfer of particular species could not be demonstrated because most species were not consistently recovered.

摘要

从执行阿波罗14号和阿波罗15号月球探索任务的6名宇航员的皮肤、喉咙、尿液和粪便中反复采集样本进行真菌学检查。飞行前数据的分析表明,在飞行前3周严格限制定植机会的过程导致分离出的物种数量减少了50%。飞行后数据表明,在太空飞行环境中暴露长达2周导致了更大幅度的减少,同时潜在病原体白色念珠菌的相对数量增加。在太空飞行完成后,机组人员被隔离16天,未观察到微生物休克的病例。由于大多数物种并非始终能被检测到,因此无法证明特定物种在机组人员之间的传播。