Folland E D, Parisi A F, Moynihan P F, Jones D R, Feldman C L, Tow D E
Circulation. 1979 Oct;60(4):760-6. doi: 10.1161/01.cir.60.4.760.
Five different algorithms for determining left ventricular (LV) ejection fraction (EF) and volumes from two-dimensional echocardiographic examination (TDE) were compared with standard methods for obtaining EF and volume from x-ray cineangiography (cine) and EF from radionuclide ventriculography (RVG) in 35 patients. Although all methods correlated positively, the degree of correlation varied with the algorithm used. For EF determination, TDE algorithms (especially those using multiple planes of section) were superior to unidimensional algorithms commonly used with M-mode echocardiography. The best algorithm (modified Simpson's rule) correlated well enough with cine EF (r = 0.78; SEE 0.097) and RVG EF (r = 0.75; SEE 0.087) to make clinically useful estimates. TDE volumes also correlated meaningfully with cine end-diastolic and end-systole volumes (r = 084; n = 70) but were associated with a large standard error of the estimate (43 ml) and offered less advantage over unidimensional volume estimates. Quantitative application of TDE appears to be a useful noninvasive method of evaluating LVEF, but is not as useful for estimating LV volumes.
在35例患者中，将用于从二维超声心动图检查（TDE）确定左心室（LV）射血分数（EF）和容积的五种不同算法，与通过X线电影血管造影术（电影）获取EF和容积以及通过放射性核素心室造影术（RVG）获取EF的标准方法进行了比较。尽管所有方法都呈正相关，但相关程度因所使用的算法而异。对于EF测定，TDE算法（尤其是那些使用多个截面平面的算法）优于通常用于M型超声心动图的一维算法。最佳算法（改良Simpson法则）与电影EF（r = 0.78；标准误差估计值[SEE] 0.097）和RVG EF（r = 0.75；SEE 0.087）的相关性良好，足以进行有临床意义的估计。TDE容积也与电影舒张末期和收缩末期容积有显著相关性（r = 0.84；n = 70），但与较大的估计标准误差（43 ml）相关，与一维容积估计相比优势较小。TDE的定量应用似乎是评估左心室射血分数的一种有用的非侵入性方法，但在估计左心室容积方面不太有用。
