在钙平衡研究中，三氧化二铬与[51Cr]氯化铬作为惰性标记物的比较。
A comparison of chromium sesquioxide and [51Cr]chromic chloride as inert markers in calcium balance studies.
作者信息
Hesp R, Williams D, Rinsler M, Reeve J
出版信息
Clin Sci (Lond). 1979 Jul;57(1):89-92. doi: 10.1042/cs0570089.
PMID:477250
Abstract
- Chromium sesquioxide (Cr2O3; 1.5 g/day) and [51Cr]chromic chloride [51CrCl3 (0.3 muCi/day)] were compared as continuously administered non-absorbed markers for the correction of faecal recoveries in 14 calcium balance studies each lasting at least 18 days. 2. The mean recoveries of each, 98.4% for Cr2O3 and 101.9% for 51CrCl3, were not significantly different from 100%. 3. The two markers reduced the uncertainity in a typical 3 x 6 day calcium balance study to a similar extent (SD = 1.4 mmol/day for Cr2O3 and SD = 1.5 mmol/day for 51CrCl3. 4. 51CrCl3 is a convenient and satisfactorily alternative to Cr2O3 when the laboratory hazards associated with estimating the latter cannot easily be eliminated.
摘要
- 在14项钙平衡研究中（每项研究至少持续18天），对作为持续施用的非吸收性标记物的三氧化二铬（Cr2O3；1.5克/天）和[51Cr]氯化铬[51CrCl3（0.3微居里/天）]进行了比较，以校正粪便回收率。2. 每种标记物的平均回收率分别为：Cr2O3为98.4%，51CrCl3为101.9%，与100%无显著差异。3. 在一项典型的3×6天钙平衡研究中，这两种标记物将不确定性降低到了相似的程度（Cr2O3的标准差为1.4毫摩尔/天，51CrCl3的标准差为1.5毫摩尔/天）。4. 当与估计Cr2O3相关的实验室危害不易消除时，51CrCl3是一种方便且令人满意的替代物。
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