Viberti G C, Jarrett R J, Watson D M, Clements C, Keen H
Diabete Metab. 1979 Jun;5(2):93-6.
Fluorescein angiography was performed in twenty three men with impaired oral glucose tolerance (borderline diabetics) and sixteen matched, normoglycaemic controls. Retinal abnormalities (microaneurysms and leakage of dye) were observed in 18.7% of the controls, 41.6% of sustained borderline diabetics and 54.4% of initially borderline diabetics who subsequently "worsened to diabetes". Qualitatively the abnormalities were similar in each group. Although the difference in frequency between the sustained borderline diabetics and the controls does not achieve conventional statistical significance, other studies quoted support the conclusion that moderate impairment of glucose tolerance is associated with a raised frequency of minor retinal abnormalities. The significance of these remains to be determined.
对23名口服葡萄糖耐量受损（临界糖尿病患者）的男性和16名匹配的血糖正常对照者进行了荧光素血管造影。在18.7%的对照者、41.6%的持续性临界糖尿病患者以及54.4%最初为临界糖尿病患者且随后“恶化成糖尿病”的患者中观察到视网膜异常（微动脉瘤和染料渗漏）。从定性角度来看，每组中的异常情况相似。尽管持续性临界糖尿病患者和对照者之间在频率上的差异未达到传统统计学显著性水平，但引用的其他研究支持这样的结论，即葡萄糖耐量的中度受损与轻微视网膜异常的频率升高有关。这些异常的意义仍有待确定。
