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慢性低水平铅暴露在智力迟钝病因学中的作用。

Role of chronic low-level lead exposure in the aetiology of mental retardation.

作者信息

Beattie A D, Moore M R, Finlayson M J, Graham J F, Mackie E M, Main J C, McLaren D A, Murdoch K M, Steward G T

出版信息

Lancet. 1975 Mar 15;1(7907):589-92. doi: 10.1016/s0140-6736(75)91879-6.

DOI:10.1016/s0140-6736(75)91879-6
PMID:47943
Abstract

Water-lead levels were measured in the homes occupied during the first year of life by 77 mentally retarded children aged two to six years and 77 non-retarded matched controls, and in the homes occupied by their mothers during pregnancy. The water-lead content was significantly higher in the retarded group, and the probability of mental retardation was significantly increased when water lead exceeded 800 mug. per litre. Blood-lead levels were also significantly higher in the retarded group. It is concluded that lead contamination of water may be one factor in the multifactorial aetiology of mental retardation and that every effort should be made to reduce the lead content of drinking-water.

摘要

对77名年龄在2至6岁的智障儿童及其77名年龄匹配的非智障对照儿童在其出生后第一年居住的家庭中以及他们母亲孕期居住的家庭中的水体铅含量进行了测量。智障儿童组家庭中的水体铅含量显著更高,当水体铅含量超过每升800微克时,智力发育迟缓的可能性显著增加。智障儿童组的血铅水平也显著更高。研究得出结论,水体铅污染可能是智力发育迟缓多因素病因中的一个因素,应尽一切努力降低饮用水中的铅含量。

相似文献

1
Role of chronic low-level lead exposure in the aetiology of mental retardation.慢性低水平铅暴露在智力迟钝病因学中的作用。
Lancet. 1975 Mar 15;1(7907):589-92. doi: 10.1016/s0140-6736(75)91879-6.
2
A retrospective analysis of blood-lead in mentally retarded children.弱智儿童血铅水平的回顾性分析。
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Lancet. 1975 Apr 26;1(7913):982-3.
4
Letter: Chronic low-level lead exposure and mental retardation.信件:慢性低水平铅暴露与智力迟钝
Lancet. 1975 May 10;1(7915):1087-8. doi: 10.1016/s0140-6736(75)91858-9.
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The neurobehavioral effects of early lead exposure.早期铅暴露的神经行为影响。
Monogr Am Assoc Ment Defic (1982). 1987(8):71-95.
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Letter: Chronic low-level lead exposure and mental retardation.信件:慢性低水平铅暴露与智力迟钝。
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Mental retardation and "nontoxic" lead levels.智力迟钝与“无毒”铅含量
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Lead as a cause of mental retardation.铅导致智力发育迟缓。
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Mental retardation and parental occupation: a study on the applicability of job exposure matrices.智力迟钝与父母职业:关于工作暴露矩阵适用性的一项研究
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Is low-level lead pollution dangerous?低水平铅污染危险吗?
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Residual effects of lead poisoning on Denver Developmental Screening Test scores.铅中毒对丹佛发育筛查测试分数的残留影响。
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