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A comparative study on the metabolism of human insulin and porcine proinsulin in man.

作者信息

Sönksen P H, Tompkins C V, Srivastava M C, Nabarro J D

出版信息

Clin Sci Mol Med. 1973 Nov;45(5):633-54. doi: 10.1042/cs0450633.

DOI:10.1042/cs0450633
PMID:4796692
Abstract
摘要

相似文献

1
A comparative study on the metabolism of human insulin and porcine proinsulin in man.人胰岛素与猪胰岛素原在人体代谢的比较研究。
Clin Sci Mol Med. 1973 Nov;45(5):633-54. doi: 10.1042/cs0450633.
2
A comparative study of the distribution and metabolism of monocomponent human insulin and porcine proinsulin in man.单组分人胰岛素和猪胰岛素原在人体中的分布及代谢的比较研究。
Biochem J. 1971 Dec;125(3):64P. doi: 10.1042/bj1250064pa.
3
The effects of biosynthetic human proinsulin on carbohydrate metabolism.生物合成人胰岛素原对碳水化合物代谢的影响。
Diabetes. 1984 Aug;33(8):762-70. doi: 10.2337/diab.33.8.762.
4
Effect of insulin induced hypoglycaemia on the blood levels of catecholamines, glucagon, growth hormone, cortisol, C-peptide and proinsulin before and during medication with the cardioselective beta-receptor blocking agent metoprolol in man.胰岛素诱导的低血糖对人体在服用心脏选择性β受体阻滞剂美托洛尔之前及期间儿茶酚胺、胰高血糖素、生长激素、皮质醇、C肽和胰岛素原血药浓度的影响。
Acta Endocrinol (Copenh). 1978 Mar;87(3):659-67. doi: 10.1530/acta.0.0870659.
5
Effect of a two hour proinsulin infusion on the glucose lowering potency of a following insulin injection.两小时胰岛素原输注对随后胰岛素注射降血糖效力的影响。
Horm Metab Res Suppl. 1988;18:34-7.
6
Comparative study of hormonal counterregulation during GCIIS-guided hypoglycemia tests using human proinsulin and human insulin (recombinant DNA).使用人胰岛素原和人胰岛素（重组DNA）在葡萄糖钳夹技术诱导的低血糖测试期间激素对抗调节的比较研究
Horm Metab Res Suppl. 1988;18:24-33.
7
Metabolism of proinsulin, insulin, and C-peptide in the rat.大鼠中胰岛素原、胰岛素和C肽的代谢
J Clin Invest. 1973 May;52(5):1113-21. doi: 10.1172/JCI107277.
8
The effects of proinsulin pretreatment on the combined actions of insulin and proinsulin in normal man.胰岛素原预处理对正常人体内胰岛素和胰岛素原联合作用的影响。
J Clin Endocrinol Metab. 1986 Apr;62(4):785-8. doi: 10.1210/jcem-62-4-785.
9
Qualitative dissimilarities of insulin and proinsulin binding and action in vitro at IM 9-lymphocytes.胰岛素和胰岛素原在IM 9淋巴细胞上体外结合及作用的定性差异
Horm Metab Res Suppl. 1988;18:89-92.
10
Measurement of serum proinsulin-like material: cross-reactivity of porcine and human proinsulin in the insulin radioimmunoassay.血清胰岛素原样物质的测定：胰岛素放射免疫分析中猪胰岛素原与人胰岛素原的交叉反应性。
J Lab Clin Med. 1978 Apr;91(4):683-92.

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Proinsulin slows retinal degeneration and vision loss in the P23H rat model of retinitis pigmentosa.胰岛素原可减缓色素性视网膜炎 P23H 大鼠模型的视网膜变性和视力丧失。
Hum Gene Ther. 2012 Dec;23(12):1290-300. doi: 10.1089/hum.2012.067. Epub 2012 Nov 5.
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Reduced insulin clearance contributes to the increased insulin levels after administration of glucagon-like peptide 1 in mice.胰岛素清除率降低导致小鼠注射胰高血糖素样肽1后胰岛素水平升高。
Diabetologia. 2005 Oct;48(10):2140-6. doi: 10.1007/s00125-005-1915-z. Epub 2005 Aug 23.
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A novel mechanism of glipizide sulfonylurea action: decreased metabolic clearance rate of insulin.格列吡嗪磺脲类药物作用的一种新机制：胰岛素代谢清除率降低。
Acta Diabetol. 1995 Dec;32(4):273-8. doi: 10.1007/BF00576262.
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Demonstration of a relatively hepatoselective effect of covalent insulin dimers on glucose metabolism in dogs.共价胰岛素二聚体对犬葡萄糖代谢的相对肝选择性作用的证明。
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Hyperinsulinemia after pancreatic transplantation. Prediction by a novel computer model and in vivo verification.胰腺移植后的高胰岛素血症。通过新型计算机模型进行预测及体内验证。
Ann Surg. 1993 Oct;218(4):428-41; discussion 441-3. doi: 10.1097/00000658-199310000-00004.
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The relationship between plasma concentration and plasma disappearance rate of immunoreactive insulin in normal subjects.正常受试者中免疫反应性胰岛素的血浆浓度与血浆消失率之间的关系。
Diabetologia. 1982 Jun;22(6):437-40. doi: 10.1007/BF00282586.