Galasko C S, Muckle D S
Br J Cancer. 1974 Jan;29(1):59-65. doi: 10.1038/bjc.1974.7.
The VX2 carcinoma has been used extensively as an experimental model for different aspects of tumour behaviour and is usually maintained by serial intramuscular injections of tumour cells. The tumour grows rapidly, infiltrating between muscle bundles into the fibrous tissue replacing ischaemic muscle and into the vascular tree. The most interesting method of spread occurs within the sarcolemma and this may be responsible for the rounded cell nests described in this tumour.
VX2癌已被广泛用作肿瘤行为不同方面的实验模型，通常通过连续肌肉注射肿瘤细胞来维持。肿瘤生长迅速，在肌束之间浸润到取代缺血肌肉的纤维组织中，并浸润到血管系统。最有趣的扩散方式发生在肌膜内，这可能是该肿瘤中出现圆形细胞巢的原因。
