Horne D S, Perry D
J Bacteriol. 1974 Jun;118(3):830-6. doi: 10.1128/jb.118.3.830-836.1974.
The effects of competence induction by competence factor (CF) on macromolecular synthesis in group H streptococcus strain Wicky were investigated. CF preparations (culture filtrates from competent group H streptococcus strain Challis) were either heated or partially purified to remove a bacteriocin. These preparations did not inhibit growth, although they induced high levels of competence in strain Wicky. The action of the CF preparations did not affect the overall rates of deoxyribonucleic acid and protein synthesis, but caused a reduction in the rates of ribonucleic acid (RNA) and peptidoglycan synthesis. When competence induction by CF was prevented, no alterations in RNA or peptidoglycan synthesis were observed, indicating that these changes are in fact related to the development of competence.
研究了用感受态因子（CF）诱导H群链球菌Wicky菌株感受态对大分子合成的影响。CF制剂（来自感受态H群链球菌Challis菌株的培养滤液）经过加热或部分纯化以去除一种细菌素。这些制剂虽然能在Wicky菌株中诱导出高水平的感受态，但并不抑制生长。CF制剂的作用不影响脱氧核糖核酸和蛋白质的总体合成速率，但导致核糖核酸（RNA）和肽聚糖合成速率降低。当阻止CF诱导感受态时，未观察到RNA或肽聚糖合成的变化，这表明这些变化实际上与感受态的发展有关。
