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人胎儿大脑中的抗坏血酸。

Ascorbic acid in fetal human brain.

作者信息

Adlard B P, De Souza S W, Moon S

出版信息

Arch Dis Child. 1974 Apr;49(4):278-82. doi: 10.1136/adc.49.4.278.

Abstract

Ascorbic acid concentrations in fetal human forebrain in the period 11 to 19 weeks' gestational age were 4 to 11 times higher than those of adults. Levels fell progressively with increasing gestational age but, in term babies dying within 4 weeks of birth, were still at least 3 times those of adults. It was confirmed that, in women delivering at term, ascorbic acid concentrations are approximately 4 times higher in cord blood plasma than in maternal blood plasma. The possible importance of ascorbic acid for normal human brain development is discussed.

摘要

孕龄11至19周的人类胎儿前脑抗坏血酸浓度比成年人高4至11倍。随着孕龄增加,其水平逐渐下降,但对于出生后4周内死亡的足月儿,该浓度仍至少是成年人的3倍。已证实,足月分娩的女性,脐带血血浆中的抗坏血酸浓度约为母血血浆中的4倍。本文讨论了抗坏血酸对人类正常脑发育的潜在重要性。

相似文献

1
Ascorbic acid in fetal human brain.人胎儿大脑中的抗坏血酸。
Arch Dis Child. 1974 Apr;49(4):278-82. doi: 10.1136/adc.49.4.278.
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Human fetal and maternal plasma oestrogens and the onset of labour.人类胎儿和母体血浆雌激素与分娩的开始
J Obstet Gynaecol Br Commonw. 1973 Nov;80(11):952-6. doi: 10.1111/j.1471-0528.1973.tb02955.x.

本文引用的文献

2
Ascorbic acid in man and animals.人类和动物体内的抗坏血酸。
Adv Clin Chem. 1961;4:121-205. doi: 10.1016/s0065-2423(08)60036-0.
3
DOPAMINE-BETA-HYDROXYLASE.多巴胺-β-羟化酶
Pharmacol Rev. 1965 Jun;17:71-100.
8
Growth and ascorbic acid content of the chick embryo.
J Embryol Exp Morphol. 1960 Dec;8:527-39.
9
Human requirements for vitamin C and its use in clinical medicine.
Ann N Y Acad Sci. 1961 Apr 21;92:230-45. doi: 10.1111/j.1749-6632.1961.tb46123.x.

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