Stafford A, Wann L S, Dillon J C, Weyman A E, Feigenbaum H
Am J Cardiol. 1979 Oct;44(4):754-60. doi: 10.1016/0002-9149(79)90298-4.
Serial M mode and cross-sectional echocardiograms were obtained from six patients who had been treated with antibiotic drugs for infectious endocarditis. Three to six M mode echocardiograms and one to six cross-sectional echocardiograms were obtained from each patient over a follow-up period averaging 50 weeks (range 10 to 108 weeks). On echocardiography, vegetations were observed to have become smaller and more echo-reflective with healing. A dramatic change was seen in two patients after peripheral embolization. M mode echocardiography was particularly helpful in determining the quality of echo reflection by vegetations; cross-sectional echocardiography was more helpful in judging the size and shape of a vegetation. Echocardiography is ideally suited for the serial visualization of healing vegetations in patients who do not require early valve replacement. It may prove helpful to examine serially valve vegetations with both M mode and cross-sectional echocardiography when following up patients with infectious endocarditis treated with antibiotic agents.
对6例因感染性心内膜炎接受抗生素治疗的患者进行了系列M型和横截面超声心动图检查。在平均50周（范围10至108周）的随访期内，为每位患者获取了3至6次M型超声心动图和1至6次横截面超声心动图。超声心动图显示，随着愈合，赘生物变小且回声增强。两名患者在发生外周栓塞后出现了显著变化。M型超声心动图在确定赘生物的回声质量方面特别有用；横截面超声心动图在判断赘生物的大小和形状方面更有帮助。超声心动图非常适合对不需要早期瓣膜置换的患者的愈合赘生物进行系列观察。在对接受抗生素治疗的感染性心内膜炎患者进行随访时，同时使用M型和横截面超声心动图对瓣膜赘生物进行系列检查可能会被证明是有帮助的。
