类风湿关节炎中的气道阻塞
Airways obstruction in rheumatoid arthritis.
作者信息
Geddes D M, Webley M, Emerson P A
出版信息
Ann Rheum Dis. 1979 Jun;38(3):222-5. doi: 10.1136/ard.38.3.222.
Abstract
Owing to the report of an association between rheumatoid arthritis (RA) and obliterative bronchiolitis we have determined the prevalence of airflow obstruction in unselected patients with RA and normal chest radiographs. Spirometry was performed on 100 patients with rheumatoid arthritis and 84 control subjects matched for age, sex, and smoking habits. Patients with rheumatoid arthritis had significantly lower values for FEV1, FVC, FEV1/FVC, and MMEFR when compared with the controls: 39 patients had abnormal spirometry, and at least 32 showed airways obstruction. The prevalence of airflow obstruction is remarkably high, and we suggest that airway disease may be the commonest form of lung involvement in rheumatoid arthritis.
摘要
由于有关于类风湿性关节炎（RA）与闭塞性细支气管炎之间关联的报告，我们测定了胸部X线片正常的未经挑选的RA患者气流阻塞的患病率。对100例类风湿性关节炎患者和84例年龄、性别及吸烟习惯相匹配的对照者进行了肺功能测定。与对照组相比，类风湿性关节炎患者的第一秒用力呼气容积（FEV1）、用力肺活量（FVC）、FEV1/FVC及最大呼气中期流速（MMEFR）值显著降低：39例患者肺功能测定异常，至少32例显示气道阻塞。气流阻塞的患病率非常高，我们认为气道疾病可能是类风湿性关节炎肺部受累最常见的形式。
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