Davis P
Ann Rheum Dis. 1979 Jun;38(3):241-3. doi: 10.1136/ard.38.3.241.
A single family is presented in which 2 of the 3 sibs and 3 of 9 first degree relatives had Crohn's disease. Two subjects with Crohn's disease had classical ankylosing spondylitis (AS), and HLA typing revealed HLA B27 in all 5 members of the immediate family. The value of quantitative sacroiliac scintigraphy (QSS) in clinical practice is demonstrated. Both patients with AS had evidence of currently active sacroiliac disease in association with radiological change. One symptomatic sib had QSS evidence of sacroiliitis without radiological abnormality.
本文报告了一个家族,该家族中3个兄弟姐妹中有2个、9个一级亲属中有3个患有克罗恩病。两名克罗恩病患者患有典型的强直性脊柱炎(AS),HLA分型显示直系亲属中的所有5名成员均为HLA B27阳性。文中展示了定量骶髂关节闪烁扫描(QSS)在临床实践中的价值。两名AS患者均有骶髂关节疾病当前活动的证据,并伴有放射学改变。一名有症状的兄弟姐妹有骶髂关节炎的QSS证据,但无放射学异常。